News & Publications for:

Abhinav Diwan

For men, low testosterone means high risk of severe COVID-19

Posted on May 25, 2021

New clues on why more men than women develop severe disease Read More

Posted in: News Faculty:

The Transcription Factor EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse AD Models

Posted on May 29, 2020

Anaïs Bécot, Raphaëlle Pardossi-Piquard, Alexandre Bourgeois, Eric Duplan, Abhinav Diwan, Jin-Moo Lee, Inger Lauritzen and Frédéric Checler, Cells, Volume 9, Issue 5, 12 May 2020 Read More

Posted in: Lysosome, Neurogenetics & Transcriptomics, Neurovascular Injury & Repair, Publications Faculty: ,

High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy

Posted on February 4, 2020

Xiangyu Zhang, Ismail Sergin, Trent D. Evans, Se-Jin Jeong, Astrid Rodriguez-Velez, Divya Kapoor, Sunny Chen, Eric Song, Karyn B. Holloway, Jan R. Crowley, Slava Epelman, Conrad C. Weihl, Abhinav Diwan, Daping Fan, Bettina Mittendorfer, Nathan O. Stitziel, Joel D. Schilling, Irfan J. Lodhi & Babak Razani. Nature Metabolism, Volume 2, Issue 1, 1 January 2020, Pages 110-125 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Publications Faculty: ,

TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy

Posted on January 21, 2020

Ali Javaheri, Geetika Bajpai, Antonino Picataggi, Smrithi Mani, Layla Foroughi, Hosannah Evie, Attila Kovacs, Carla J. Weinheimer, Krzystztof Hyrc, Qingli Xiao, Andrea Ballabio, Jin-Moo Lee, Scot J. Matkovich, Babak Razani, Joel D. Schilling, Kory J. Lavine, and Abhinav Diwan. JCI Insight, Volume 4, Issue 21, 1 November 2019, Article number e127312 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: ,

Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival

Posted on June 11, 2019

John T. Murphy , Haiyan Liu , Xiucui Ma, Alex Shaver, Brian M. Egan, Clara Oh, Alexander Boyko, Travis Mazer, Samuel Ang, Rohan Khopkar, Ali Javaheri, Sandeep Kumar, Xuntian Jiang, Daniel Ory, Kartik Mani, Scot J. Matkovich, Kerry Kornfeld , Abhinav Diwan. PLoS biology, Volume 17, Issue 5, 1 May 2019, Page e3000245 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Publications Faculty: