Until further notice, Hope Center/Department of Neurology Monday Noon Seminars will be on Zoom

Mini-series topics are selected by the Hope Center Steering Committee from suggestions made by the Washington University community. Each mini-series is comprised of 4-5 weekly seminars, with talks by Washington University investigators as well as investigators at other institutions who are leaders in their fields.

Have an idea for a mini-series topic? Let us know!

Deadline to submit topic suggestions for the 2023/2023 season is Wednesday, February 22!


2022/2023 Monday Noon Seminars

Mondays, 12-1p
September – June
Zoom conference (*unless noted)


Current mini-series

Role of the Adaptive/Innate Immune System in Neurodegeneration
Organizer: David Holtzman (WashU Neurology)

  • January 9: Xiaoying Chen (Holtzman lab, WashU Neurology) “Mapping neuro-immune states in Alzheimer’s Disease”
  • January 23: David Gate (Northwestern University) “Cerebrospinal fluid immunity in healthy brain aging and neurodegenerative disease”
  • January 30: Marco Colonna (WashU Pathology & Immunology) “Different impacts on the CNS of TREM2 deficiencies in human and mouse”
  • February 6: Naresha Saligrama (WashU Neurology) “Description of peripheral and central immunological responses to neuronal antigens”

Click here for Zoom information (WUSTL Key required)

Full schedule of mini-series topics
2022/2023

Click below to view dates, speakers and talk titles.

Hormones in Brain Function and Disease
Organizers: John Cirrito, Rachel Hendrix, Hannah Edwards (WashU Neurology)
  • October 3: Carla Yuede (WashU Psychiatry) “Stress as a risk factor for sex-dependent differences in Alzheimer’s disease”
  • October 10: Steven Mennerick (WashU Psychiatry) “The impact of neurosteroids on the brain: Where is the therapeutic benefit?”
  • October 17: Kristen Zuloaga (Albany Medical College) “Influence of sex and endocrine aging on vascular and metabolic contributions to dementia”
Human Genetics of Neurological Disorders
Organizers: Celeste Karch (WashU Psychiatry) and Gabe Haller (WashU Neurosurgery)
  • October 31: Christina Gurnett (WashU Neurology) “High throughput testing of functional variants to improve patient selection for clinical trials”
  • November 7: Kristen Brennand (Yale School of Medicine) “Using Stem Cells to Explore the Genetics Underlying Brain Disease”
  • November 21: Tychele Turner (WashU Genetics) “Precision genomics as a key component for the future of precision medicine”
  • November 28: Carlos Cruchaga (WashU Psychiatry) “Cerebrospinal fluid proteogenomic analyses: Identification of novel proteins and therapeutic targets for Alzheimer’s and Parkinson’s disease”
  • IN-PERSON* – December 5: Kaitlin Samocha (Massachusetts General Hospital) “Contribution of rare variation to developmental disorders”
  • December 12: Joseph Dougherty (WashU Genetics) “High throughput assays to understand the function of psychiatric disease variants in the brain”  

Role of the Adaptive/Innate Immune System in Neurodegeneration
Organizer: David Holtzman (WashU Neurology)
  • January 9: Xiaoying Chen (Holtzman lab, WashU Neurology) “Mapping neuro-immune states in Alzheimer’s Disease”
  • January 23: David Gate (Northwestern University) “Cerebrospinal fluid immunity in healthy brain aging and neurodegenerative disease”
  • January 30: Marco Colonna (WashU Pathology & Immunology) “Different impacts on the CNS of TREM2 deficiencies in human and mouse”
  • February 6: Naresha Saligrama (WashU Neurology) “Description of peripheral and central immunological responses to neuronal antigens”

Metabolic Dysregulation in Neurodegeneration
Organizer: Ghazal Ashrafi (WashU Cell Biology & Physiology)
  • February 27
  • March 6
  • March 13
  • March 20

Fundamental Mechanisms of Aging on Neurodegeneration
Organizer: Randall Bateman (WashU Neurology)
  • March 27
  • April 3
  • April 10
  • April 17

Gene Therapy and CNS disorders
Joint series with the Department of Developmental Biology
Organizer: Patricia Dickson (WashU Pediatrics)
  • May 1
  • May 8
  • May 22

Special Seminars
  • Special Hope Center/Neurology Seminar (12p, Holden Auditorium and Zoom)
    • February 20: Jeffrey Savas (Northwestern University)
  • Date TBA: Presentations by winners of the 2023 Hope Center Awards

Seminars also are listed on the ONR Calendar.