Organizers: Hiroko Yano, Fumihiko Urano, Albert Kim
Mission
To restore neurological function in patients suffering from diseases that impact the human nervous system through the development of novel multidisciplinary therapeutic strategies.
Strategies
- Development and implementation of clinical trials for patients with neurological diseases using regenerative medicine-, cell-, drug-, and virus-based approaches
- Development of patient tissue-derived models of human diseases
- Understanding disease mechanisms using cell and animal models to translate findings to human diseases
Target disease areas
- Neurodegenerative diseases, including diseases of the eye
- Spinal cord injury
- Brain tumors
- Neurodevelopmental disorders
Specific neurological diseases of interest include Amyotrophic lateral sclerosis, Huntington’s disease, Parkinson’s disease, Wolfram syndrome, spinal cord injury, and brain tumors (glioblastoma, meningioma, pituitary tumors)
2025 Schedule
1st Wednesday of the month
12:00p – 1:00p
Zoom conference
For inquiries or to be added to the NRTG Outlook Zoom distribution list contact the Hope Center.
- January 8*: Yunshuo Tang (WashU Neurology) “NF1-associated optic glioma: From Bedside to Bench to Bedside”
*2nd Wednesday - February 5: Andrew Yoo (WashU Developmental Biology) “Molecular logic underlying neuronal reprogramming of human somatic cells and neurodegeneration modeling”
- March 5: Jeffrey Millman (WashU Medicine) “Disease Modeling Using Human Organoids”
- April 2: Guoyan Zhao (WashU Genetics/WashU Neurology) “Single-Cell Genomics Illuminates Convergent Molecular Mechanisms and Drug Targets in Neurodegeneration Across Six Diseases and Seven Brain Regions”
- May 7: Farzané Mirfakhar (Karch lab, WashU Psychiatry) “Cellular Cleanup Gone Awry: Tau accumulation in a stem cell model of tauopathy”
For previous years’ presentations, check out the archives link below.
All meetings are listed on the ONR Calendar of the Office of Neuroscience Research.
- September 4: Kristen Kroll (WashU Developmental Biology) “Altered transcriptional and epigenetic regulation in the etiology of neurodevelopmental disorders”
- October 2: Jonathan Lin (Stanford University) “Genetic variation of the Unfolded Protein Response in human diseases”
- November 6: Samagya Banskota (Boston University) “Advancing precision genome editing therapeutics through delivery”
- December 4: William Buchser (WashU Genetics) “Image Analysis Tools for Single Neurons in Functional Genomics”
Sarah Ackerman (WashU Pathology & Immunology)
Asher Albertson (WashU Neurology)
Rajendra Apte (WashU Ophthalmology & Visual Sciences)
Laura Campisi (WashU Pathology & Immunology)
Hong Chen (WashU Biomedical Engineering and WashU Neurosurgery)
Mai Dang (WashU Neurology)
Patricia Dickson (WashU Pediatrics)
Claudia Han (WashU Pathology & Immunology)
Masatoshi Inoue (WashU Radiology)
Albert Kim (WashU Neurosurgery)
Jonathan Kipnis (WashU Pathology & Immunology)
Terrance Kummer (WashU Neurology)
Eric Landsness (WashU Neurology)
Eric Lenze (WashU Psychiatry)
Timothy Miller (WashU Neurology)
Jeffrey Millman (WashU Medicine)
Camilo Molina (WashU Neurosurgery)
Andrew Nguyen (Saint Louis University)
Grace Niziolek (WashU Surgery)
Cynthia Ortinau (WashU Pediatrics)
Zack Ray (WashU Neurosurgery)
Maria Remedi (WashU Medicine)
Jennifer Strahle (WashU Neurosurgery)
Fumihiko Urano (WashU Medicine)
Hiroko Yano (WashU Neurosurgery)
Andrew Yoo (WashU Developmental Biology)
Guoyan Zhao (WashU Genetics and WashU Neurology)