News & Publications for:

Paul Kotzbauer

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

Posted on November 23, 2020

Laura Ibanez, Jorge A. Bahena, Chengran Yang, Umber Dube, Fabiana H. G. Farias, John P. Budde, Kristy Bergmann, Carol Brenner-Webster, John C. Morris, Richard J. Perrin, Nigel J. Cairns, John O’Donnell, Ignacio Álvarez, Monica Diez-Fairen, Miquel Aguilar, Rebecca Miller, Albert A. Davis, Pau Pastor, Paul Kotzbauer, Meghan C. Campbell, Joel S. Perlmutter, Herve Rhinn, Oscar Harari, Carlos Cruchaga & Bruno A. Benitez. Acta Neuropathologica Communications volume 8, Article number: 196 (2020) Read More

Posted in: Axon Injury & Repair, Clocks & Sleep, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , , , ,

Proteinopathy and longitudinal changes in functional connectivity networks in Parkinson disease

Posted on May 29, 2020

Meghan C. Campbell, Joshua J. Jackson, View ORCID ProfileJonathan M. Koller, Abraham Z. Snyder, Paul T. Kotzbauer, Joel S. Perlmutter. Neurology, Volume 94, Issue 7, 18 February 2020, Pages e718-e728 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: ,

Sleep Deprivation Affects Tau Phosphorylation in Human Cerebrospinal Fluid

Posted on March 18, 2020

Nicolas R. Barthélemy, Haiyan Liu, William Lu, Paul T. Kotzbauer, Randall J. Bateman, Brendan P. Lucey. Annals of Neurology 2020 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: , ,

APOE genotype regulates pathology and disease progression in synucleinopathy

Posted on February 20, 2020

Albert A. Davis, Casey E. Inman, Zachary M. Wargel, Umber Dube, Brittany M. Freeberg, Alexander Galluppi, Jessica N. Haines, Dhruva D. Dhavale, Rebecca Miller, Fahim A. Choudhury, Patrick M. Sullivan, Carlos Cruchaga, Joel S. Perlmutter, Jason D. Ulrich, Bruno A. Benitez, Paul T. Kotzbauer and David M. Holtzman. Science Translational Medicine, Volume 12, Issue 529, 5 February 2020 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , ,

Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation

Posted on May 17, 2019

Rachel L. French, Zachary R. Grese, Himani Aligireddy, Dhruva D. Dhavale, Ashley N. Reeb, Niraja Kedia, Paul T. Kotzbauer, Jan Bieschke and Yuna M. Ayala. Journal of Biological Chemistry, Volume 294, Issue 17, 2019, Pages 6696-6709 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: ,