Cooper receives two NIH grants to study rare genetic disease

Jonathan D. Cooper, PhD,  a professor of pediatrics, of genetics and of neurology at the Washington University School of Medicine in St. Louis, received two grants totaling $2.55 million over five years from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health (NIH).  Cooper will study enzyme replacement therapy as a possible […]

Puri wins postdoctoral fellowship to study ALS

Anuradhika Puri, PhD, a postdoctoral research associate working with Meredith Jackrel, PhD in the Department of Chemistry in Arts & Sciences at Washington University in St. Louis, won the Amyotrophic Lateral Sclerosis Association’s Milton Safenowitz Postdoctoral Fellowship. The $150,000 award supports her work on applying the human disaggregase, HtrA1, to counter amyotrophic lateral sclerosis, or ALS. Originally published on […]

Researchers studying links between retinal appearance, Alzheimer’s

Four years after Washington University in St. Louis researchers detected a possible link between risk for Alzheimer’s disease and the appearance of the eye’s retina, a $10.3 million grant from the National Institute on Aging of the National Institutes of Health (NIH) is expanding the effort to understand that connection. Gregory P. Van Stavern, MD, […]

Holy awarded grant to study mouse pheromones

For animals such as mice, olfaction is their primary route to pick up social information, whether that’s identifying the dominant male in a group or figuring out the reproductive status of females. In turn, these signals can influence animals’ behavior and physiology. Pheromones in male urine, for instance, can trigger early puberty in mice. While […]

Pappu lab untangles more IDR secrets

Intrinsically disordered regions (IDRs) of proteins, when tethered to folded domains, function either as flexible tails or as linkers between domains. Most IDRs are composed of a mixture of oppositely charged residues. Recent measurements of tethered polyampholytes have shown that arginine- and lysine-rich sequences tend to behave very differently from one another. In a paper […]

Yoo wins research grants

Two-year $486,844 grant from Brigham and Women’s Hospital and a two-year $345,000 grant from the Cure Alzheimer’s Fund