This episode of ‘Show Me the Science’ focuses on approval of a drug that attacks a key protein that contributes to dementia from Alzheimer’s disease
Podcast: Newly approved drug may slow progression of Alzheimer’s

This episode of ‘Show Me the Science’ focuses on approval of a drug that attacks a key protein that contributes to dementia from Alzheimer’s disease
Nearly every person with Down syndrome eventually develops Alzheimer’s disease, yet people with the syndrome routinely are excluded from Alzheimer’s clinical trials, as the cognitive assessment tools designed for the general population often are inappropriate for people with developmental disabilities. Consequently, nobody knows whether the new Alzheimer’s therapeutics hitting the market will work for people […]
Test results available in less than a minute
Two pathologies drive the progression of Alzheimer’s disease. Early on, amyloid beta plaques lead the way, but around the time cognitive symptoms arise, tau tangles take over as the driving force and cognition steadily declines. Tracking the course of the disease in individual patients has been challenging because there’s been no easy way to measure […]
Grant will support research on brain plasticity
People in the earliest stage of Alzheimer’s disease — after brain changes have begun but before cognitive symptoms become apparent — harbor an assortment of bacteria in their intestines that differs from the gut bacteria of healthy people, according to a study by researchers at Washington University School of Medicine in St. Louis. The findings, […]
Microbiome pioneer Jeffrey I. Gordon, MD, of Washington University School of Medicine in St. Louis, has won the 2023 Princess of Asturias Award for Technical and Scientific Research. The Asturias awards, among the most prestigious honors in the Spanish-speaking world, are presented annually in eight categories. The awards are designed to recognize exceptional scientific, technical, cultural, […]
Diabetes researchers at Washington University School of Medicine in St. Louis have uncovered at least one reason insulin-secreting cells made from stem cells in the lab don’t work as well as natural cells. The discovery could help speed progress toward making insulin-secreting cells — called islet beta cells — more effective in the treatment of […]
Recognized for contributions to Alzheimer’s disease research
A new drug has been approved by the Food and Drug Administration (FDA) for a rare, inherited form of amyotrophic lateral sclerosis (ALS), a paralyzing neurological disease. Known as tofersen, the drug has been shown to slow progression of the deadly disease. International clinical trials of tofersen, developed by the global biotechnology company Biogen Inc., […]
More research needed to determine if sleep medications prevent, delay Alzheimer’s
Findings could lead to universal therapies for alcohol, tobacco, cannabis, opioid addictions
Honored for work developing new kind of therapy for neurodegenerative diseases
‘Father of the field’ honored for gut microbiome research
Funding from NIH HEAL Initiative
Enzyme replacement therapy, in mice and sheep, slowed brain degeneration
Researchers from several labs to study role of transposable elements
Recognizes scientist’s contributions to Alzheimer’s disease research
Could aid efforts to find treatments for Alzheimer’s, other diseases
‘We are all doing important work’
Carlos Cruchaga, PhD, a pioneer in the use of human genomic data to understand and elucidate the biology of neurodegenerative diseases such as Alzheimer’s disease, has been named an inaugural Barbara Burton and Reuben M. Morriss III Professor at Washington University School of Medicine in St. Louis. Cruchaga was installed by Chancellor Andrew D. Martin […]
The American Society of Hematology has honored John Atkinson, MD, the Samuel Grant Professor of Medicine at Washington University School of Medicine in St. Louis, for his significant contributions to the field of hematology. He is one of two recipients of the Ernest Beutler Lecture and Prize and is recognized for breakthroughs that have advanced understanding […]
Neuroscience leaders and other faculty and staff at Washington University School of Medicine in St. Louis got an up-close look at the Neuroscience Research Building during a recent tour of the construction site. The framework of all 11 stories has been built, and the process of wrapping the building in glass is underway. On the […]
A new study from Washington University School of Medicine in St. Louis demonstrates that certain human gut microbes can mine dietary fiber to extract nutrients that otherwise would remain inaccessible to the human body. The study, published June 27 in the journal Cell, illustrates how the fiber byproducts of food production — such as rinds, peels […]
Hyperactive neurons drive tumor growth in NF1 cancer predisposition syndrome
Similar to itch, pleasant touch transmitted by specific neuropeptide and neural circuit
New data prompts reconsideration of decades-old theory about brain injury due to stroke
3 of 4 tests performed inconsistently across racial groups
Diagnosing, treating sleep apnea may make driving safer for older adults
Kravitz, others honored by Office of Postdoctoral Affairs
Findings will encourage more data sharing, collaboration among researchers
Neurosurgeon Albert H. Kim is nationally recognized expert on brain tumors
New method has potential for helping diagnose Alzheimer’s before symptoms develop
Multicenter team aims to understand how, why brain changes with age
When combined with genetic risk factors, test up to 93% accurate at identifying people at risk of Alzheimer’s dementia
Treatment with interleukin-7 revs up immune system against deadly brain tumor
Major international initiative renamed in honor of Knight family
Focus on inherited Alzheimer’s up to 25 years before expected dementia onset
Mouse study IDs immune cells as link, points to potential therapeutic approaches
Low-cost drug lowers risk of hospitalizations, deaths
Drugs targeting amyloid, tau to be evaluated together
Research to explore the effects of social isolation on cognitive, emotional health
Too little and too much sleep linked to cognitive decline
Targeting support cells with cholesterol drug could improve recovery after spinal cord injury
Complements efforts of Taylor Family Institute to develop treatments for psychiatric illness
International team seeks hidden signs of brain damage in REM behavior disorder
Alzheimer’s dementia predicted by brain amyloid levels, age
International foundation honors work on gut microbiome research
Weekly saliva tests contributed to low rates during previous school year
Research program investigates link between viral infections, memory problems