Key steps leading to such accumulation identified; could inform new therapeutic approaches
How do toxic proteins accumulate in Alzheimer’s and other diseases?
Category: Axon Injury & Repair
Fast ‘yes’ better for brain than slow ‘no’
Mechanical engineers find brain’s vulnerability to head motion depends on direction and frequency, not just impact strength
Brain movement measured for clues to prevent, reduce injury
When the human head experiences any kind of movement — from nodding yes or no to heading a soccer ball or being jolted in a car crash — the brain moves inside the skull, leading to deformation of the tissue. Such deformations are key to understanding traumatic brain injury but are challenging to study since […]
Ackerman named a 2023 Klingenstein-Simons fellow
Grant will support research on brain plasticity
Bagnall wins grant to map neuronal connections
Martha Bagnall, PhD, an assistant professor of neuroscience at Washington University School of Medicine in St. Louis, received a $1.9 million R01 grant from the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health (NIH), to map neuronal connections in the zebrafish spinal cord. The Bagnall lab studies motor control […]
Mind-body connection is built into brain, study suggests
Findings point to brain areas that integrate planning, purpose, physiology, behavior, movement
Challenges With Tailoring Diets in Multiple Sclerosis: Laura Piccio, MD, PhD
The neurologist and physician scientist at Washington University in St. Louis provided insight on the general dieting strategies patients with multiple sclerosis should take as more information becomes available. [WATCH TIME: 6 minutes]
Disrupted flow of brain fluid may underlie neurodevelopmental disorders
New imaging technique reveals circulation patterns in developing brain
Cooper receives two NIH grants to study rare genetic disease
Jonathan D. Cooper, PhD, a professor of pediatrics, of genetics and of neurology at the Washington University School of Medicine in St. Louis, received two grants totaling $2.55 million over five years from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health (NIH). Cooper will study enzyme replacement therapy as a possible […]
Researchers studying links between retinal appearance, Alzheimer’s
Four years after Washington University in St. Louis researchers detected a possible link between risk for Alzheimer’s disease and the appearance of the eye’s retina, a $10.3 million grant from the National Institute on Aging of the National Institutes of Health (NIH) is expanding the effort to understand that connection. Gregory P. Van Stavern, MD, […]
Immunotherapy eliminates disease-causing cells in mice with MS-like disease
Successful cancer treatment approach extended to autoimmune disease
Rejuvenated immune cells can improve clearance of toxic waste from brain
Findings in mice suggest new therapeutic approach to Alzheimer’s, other age-related diseases
Understanding, treating pain, reducing opioid use, aim of $11.7 million grant
Funding from NIH HEAL Initiative
New strategy shows potential to block nerve loss in neurodegenerative diseases
Research into how key molecule triggers axon death may lead to new therapies
Multi-scale imaging technique may enable objective assessment of myofascial pain
Song Hu, Yong Wang team up to find quantitative biomarkers for clinical pain management
Research offers clues for treating fatal neurological disorder in kids
Enzyme replacement therapy, in mice and sheep, slowed brain degeneration
Protein linked to intellectual disability has complex role
Finding therapies for fragile X may depend on understanding the many ways protein’s loss affects brain
Rutherford to study noise-induced hearing loss
$3.5M grant from NIH
Bayly-led team to study mechanical strains, stresses in traumatic brain injury
Philip Bayly, collaborators to use imaging, modeling to look at waves in the brain
DiAntonio, Bloom, Milbrandt win ALS grant
Two-year $300,000 grant
Diabetes, metabolic syndrome in mice treated with novel class of compounds
Improves insulin secretion, lowers blood sugar
Kerschensteiner to research visual pathways
Five-year $2 million grant from NIH
Covey, Milbrandt, Moran named to National Academy of Inventors
Faculty members honored for ‘highly prolific spirit of innovation’
Board grants faculty appointments, promotions, tenure
At the Washington University in St. Louis Board of Trustees meeting Oct. 1, numerous faculty members were appointed or promoted with tenure or granted tenure, effective that day. Promotion with tenure Su-Hsin Chang, PhD, to associate professor of surgery (public health services) at the School of Medicine; Milan G. Chheda, MD, to associate professor of medicine […]
Drug helps sensory neurons regrow in the mouse central nervous system
Targeting support cells with cholesterol drug could improve recovery after spinal cord injury
$12.2 million to fund new Conte Center to study neurosteroids
Complements efforts of Taylor Family Institute to develop treatments for psychiatric illness
Memory disorders after viral infections focus of $8.7 million grant
Research program investigates link between viral infections, memory problems
Studies reveal skull as unexpected source of brain immunity
Immune cells from skull bone marrow guard the brain, spinal cord