Jeffrey I. Gordon, MD, the Dr. Robert J. Glaser Distinguished University Professor at Washington University School of Medicine in St. Louis, has been awarded the 21st annual Nierenberg Prize from the Scripps Institution of Oceanography at the University of California, San Diego. The prize is awarded for outstanding contributions to science in the public interest. Gordon, director […]
Mouse study shows engineered immune cell therapy protects damaged neurons
Findings could point to new strategies to treat Alzheimer’s
The Research Development Office in the Office of the Vice Chancellor for Research is pleased to announce the final awardees from FY 2024 of the Here and Next Seed Grant Program. The program’s broad goal is to encourage novel, innovative interdisciplinary research excellence amongst Washington University researchers on both the Med School and Danforth Campuses. […]
Detailed blueprint of nerve cells’ dramatic changes could help identify ways to heal spinal cord damage
Washington University School of Medicine faculty members Mark Rutherford and Yang E. Li have won grants from St. Baldrick’s Foundation to study pediatric cancers.
Scientists at the McKelvey School of Engineering at Washington University in St. Louis sort the rules governing putty-like biomolecular condensates.
With new technique, patient-derived neurons accurately model late-onset Alzheimer’s, point to potential treatments
Head-to-head comparison of six tests reveals which ones could replace spinal taps, brain scans
Researchers at Washington University School of Medicine in St. Louis have shown how brain tumors evolve in response to therapy, helping describe how such cancers develop treatment resistance that leads to the high mortality rate characteristic of this cancer. Only 5% of patients survive five years after diagnosis with the most aggressive brain cancers. Published […]
mans and other animals, signals from a central circadian clock in the brain generate the seasonal and daily rhythms of life. They help the body to prepare for expected changes in the environment and also optimize when to sleep, eat and do other daily activities. Scientists at Washington University in St. Louis are working out […]
Study advances efforts to harness drug’s mind-altering power to treat mental illness
Howard Hughes Medical Institute honors duo’s research
Professors honored for research, service, teaching, community contributions
Scientists are trying to understand how cannabis may affect long-term neurodevelopment when people were exposed to it in the womb. Previous work by Washington University in St. Louis researchers Sarah Paul and David Baranger in the Behavioral Research and Imaging Neurogenetics (BRAIN) lab led by Ryan Bogdan, PhD, found associations between prenatal cannabis exposure and potential mental health conditions in childhood […]
Brian A. Gordon, PhD, an assistant professor of radiology at Washington University School of Medicine in St. Louis and a principal investigator in the Mallinckrodt Institute of Radiology (MIR)’s Neuroimaging Labs Research Center, was selected for the 2024 New Investigator Award from the National Alzheimer’s Coordinating Center and the Alzheimer’s Association. This award is given […]
Yao Chen, PhD, an assistant professor of neuroscience at Washington University School of Medicine in St. Louis, is part of two teams that have been awarded grants to study the molecular processes that underlie memory and cognition. The grants are part of the “Research Corporation for Science Advancement’s Scialog: Molecular Basis of Cognition” initiative. The […]
Clinical trial for RVCL-S patients tests drug already approved as sickle cell disease treatment
The brain needs to flush out waste products to stay healthy and fend off conditions like Alzheimer’s disease. Scientists are beginning to understand how the the brain’s waste removal system works. [Transcript] A MARTÍNEZ, HOST: Turns out the brain needs regular cleaning. Otherwise, it gets clogged up with waste products, including some associated with diseases […]
Human brain diseases, such as Parkinson’s disease, involve damage in more than one region of the brain, requiring technology that could precisely and flexibly address all affected regions simultaneously. Researchers at Washington University in St. Louis have developed a noninvasive technology combining a holographic acoustic device with genetic engineering that allows them to precisely target […]
There is increasing evidence that the immune system is involved in the development and progression of Alzheimer’s disease. Most research has focused on the innate immune system and its role in mediating neuroinflammation and degeneration. Naresha Saligrama, PhD, an assistant professor of neurology at Washington University School of Medicine in St. Louis, has received a […]
Morby prize from Cure Alzheimer’s Fund honors discovery of T cells’ role in neurodegeneration
The one-year awards promote collaborative research within the university
Roughly one in five cancer patients benefits from immunotherapy – a treatment that harnesses the immune system to fight cancer. Such an approach to beating cancer has seen significant success in lung cancer and melanoma, among others. Optimistic about its potential, researchers are exploring strategies to improve immunotherapy for cancers that don’t respond well to […]
Study reveals mechanism for why treatment appears to work better in the morning
The research by Phil Bayly’s lab makes cover of Journal of the Acoustical Society of America
A study in mice by researchers at the School of Medicine indicates that brain injury can lead to brain tumors in susceptible individuals. For this study, they used mice that model people with neurofibromatosis type 1 (NF1), a genetic disorder that causes brain tumors. The study showed that molecules released by injured neurons set off […]
Abhinav Diwan, MD, a highly regarded cardiologist with expertise in the molecular underpinnings of cardiovascular disease, has been named the inaugural Charlie W. Shaeffer, MD, Professor of Cardiology at Washington University School of Medicine in St. Louis. Diwan was installed by David H. Perlmutter, MD, executive vice chancellor for medical affairs, the George and Carol […]
Nine researchers at Washington University School of Medicine in St. Louis have received funding from the Longer Life Foundation — a cooperative effort between the School of Medicine and the Reinsurance Group of America. The foundation supports research aimed at improving human health, wellness and longevity. The researchers are: Originally published on The Source.
Each year, the Hope Center for Neurological Disorders recognizes trainees (students and postdocs) who present their work at the Hope Center Retreat. Hope Center award winners are selected based on scientific merit, presentation, and projects that address the Hope Center mission. Congratulations to the winners of this year’s Hope Center Awards! Winner from the talks: Vishnu Muraleedharan Saraswathy, […]
Three physician-scientists at Washington University School of Medicine in St. Louis have been newly elected to the Association of American Physicians. Membership in the organization is an honor bestowed on physicians who lead innovative scientific research to improve health care. They are Patricia I. Dickson, MD, Dineo Khabele, MD, and Gregory D. Longmore, MD. Dickson, the Centennial Professor […]
Gift from Andy Newman supports world-changing research on the gut microbiome
Study highlights need to develop therapies for this vulnerable population
Study lays groundwork for clinical trial aimed at preventing brain tumors in children with NF1
At the Washington University in St. Louis Board of Trustees meeting March 1, numerous faculty members were appointed with tenure, promoted with tenure or granted tenure. Their new roles and titles take effect July 1, unless otherwise indicated. Appointment with tenure Steven Miles as a professor of history in Arts & Sciences. Granting of tenure Paul […]
For the past several years, Washington University in St. Louis researchers have been using focused ultrasound combined with microbubbles to target an opening in the tough, protective blood-brain barrier to deliver drugs or retrieve biomarkers. To ensure that the fast-developing technology functions safely and consistently, Hong Chen, PhD, and her team, including first author and […]
Popular alternative to CPAP machines may not be appropriate for all
Alzheimer’s disease starts with a sticky protein called amyloid beta that builds up into plaques in the brain, setting off a chain of events that results in brain atrophy and cognitive decline. The new generation of Alzheimer’s drugs — the first proven to change the course of the disease — work by tagging amyloid for […]
Researchers aim to create treatment that promotes tissue regeneration, restores joints
Scientists trying to understand the physical and chemical properties that govern biomolecular condensates now have a crucial way to measure pH and other emergent properties of these enigmatic, albeit important cellular compartments. Condensates are communities of proteins and nucleic acids. They lack a membrane and come together and fall apart as needed. The nucleolus is […]
Hong Chen, Jon Silva, both in biomedical engineering, are honored as rising leaders in their fields
There lies a paradox in sleep. Its apparent tranquility juxtaposes with the brain’s bustling activity. The night is still, but the brain is far from dormant. During sleep, brain cells produce bursts of electrical pulses that cumulate into rhythmic waves — a sign of heightened brain cell function. But why is the brain active when we […]
First-in-human trial demonstrates safety of sonobiopsy in patients with glioma Getting a biopsy is often an important first step for cancer diagnosis and treatment. But brain tumors present unique challenges: to perform a biopsy, a neurosurgeon will likely need to drill into the skull, and removing brain tissue can cause complications, including bleeding, brain swelling, […]
Neurologist studies role of sleep in neurodegenerative diseases
Could make early Alzheimer’s diagnosis, treatment accessible to more people
High-tech imaging tool could be used in other medical fields
Jeffrey I. Gordon, MD, of Washington University School of Medicine in St. Louis, has received the 2024 Mechthild Esser Nemmers Prize in Medical Science from Northwestern University. Gordon was selected for the prize by a jury of distinguished U.S. scientists for transforming the understanding of human health and how it is shaped by the gut […]
Discovered route serves as passageway to clear fluid waste from brain
Dozens of noted scientists, philanthropists, and university, state and local leaders gathered Jan. 18 to celebrate the dedication of one of the world’s largest neuroscience research buildings, a gleaming state-of-the-art facility on the Washington University Medical Campus. They toured its sophisticated, newly christened labs; listened intently as Washington University scientists described the lifesaving work they […]
Honor named after mentor, former head of neurosurgery department