Findings could lead to universal therapies for alcohol, tobacco, cannabis, opioid addictions
Multiple substance use disorders may share inherited genetic signature

Findings could lead to universal therapies for alcohol, tobacco, cannabis, opioid addictions
Findings, in mice, open up drug development possibilities for brain diseases linked to tau protein
For older adults with clinical depression that has not responded to standard treatments, adding the drug aripiprazole (brand name Abilify) to an antidepressant they’re already taking is more effective than switching from one antidepressant to another, according to a new multicenter study led by Washington University School of Medicine in St. Louis. Aripiprazole originally was […]
Honored for work developing new kind of therapy for neurodegenerative diseases
The neurologist and physician scientist at Washington University in St. Louis provided insight on the general dieting strategies patients with multiple sclerosis should take as more information becomes available. [WATCH TIME: 6 minutes]
Funding from the National Institutes of Health will help Jackrel and her team study Matrin-3, a poorly understood protein linked to several neurodegenerative disorders.
New imaging technique reveals circulation patterns in developing brain
Jonathan D. Cooper, PhD, a professor of pediatrics, of genetics and of neurology at the Washington University School of Medicine in St. Louis, received two grants totaling $2.55 million over five years from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health (NIH). Cooper will study enzyme replacement therapy as a possible […]
Research could facilitate diagnosis of Alzheimer’s disease
‘Father of the field’ honored for gut microbiome research
Hope Happens, collaborative partner of the Hope Center, is hosting the 17th Annual Evening of Hope Gala on Saturday, May 6, 2023, at the Hall at Olive+Oak in Webster Groves. Hope Happens will honor the work of Hope Center faculty members, Aaron DiAntonio and Jeffrey Milbrandt. The Charles Glenn Group will be the featured entertainment […]
Research from labs of Rohit Pappu, collaborators sheds light on condensate characteristics
Findings suggest new approach to treating Alzheimer’s, other neurodegenerative diseases
Anuradhika Puri, PhD, a postdoctoral research associate working with Meredith Jackrel, PhD in the Department of Chemistry in Arts & Sciences at Washington University in St. Louis, won the Amyotrophic Lateral Sclerosis Association’s Milton Safenowitz Postdoctoral Fellowship. The $150,000 award supports her work on applying the human disaggregase, HtrA1, to counter amyotrophic lateral sclerosis, or ALS. Originally published on […]
At the Washington University in St. Louis Board of Trustees meeting Dec. 2, several faculty members were granted tenure. Their new roles took effect Dec. 2. Granting of tenure Marlon M. Bailey as professor of African and African American studies and of women, gender, and sexuality studies, both in Arts & Sciences; Adam Q. Bauer, PhD as […]
Four years after Washington University in St. Louis researchers detected a possible link between risk for Alzheimer’s disease and the appearance of the eye’s retina, a $10.3 million grant from the National Institute on Aging of the National Institutes of Health (NIH) is expanding the effort to understand that connection. Gregory P. Van Stavern, MD, […]
Focus is on therapies for Alzheimer’s, other neurodegenerative diseases
Successful cancer treatment approach extended to autoimmune disease
“These trials don’t go without huge input and commitment from the participants and of course, their caregivers, and the clinical trial sites. I have the privilege of speaking to you about the trial as the lead author of this paper, but this is a team effort and includes a large group of people from multiple […]
Findings could help explain rare symptoms such as problems with language, vision
Installation talk, titled “For Whom the Bells Toll: Networked Circadian Clocks and Clock Watchers”
Findings in mice suggest new therapeutic approach to Alzheimer’s, other age-related diseases
Hope Center members Gabel and Rutherford granted tenure
Symposium brings together key leaders in the field
Funding from NIH HEAL Initiative
An idea that has propelled Alzheimer’s research for more than 30 years is approaching its day of reckoning. Scientists are launching a study designed to make or break the hypothesis that Alzheimer’s is caused by a sticky substance called beta-amyloid. The study will give an experimental anti-amyloid drug to people as young as 18 who […]
Neurons made from Huntington’s disease patients’ skin cells shed light on cognitive decline
Research into how key molecule triggers axon death may lead to new therapies
Song Hu, Yong Wang team up to find quantitative biomarkers for clinical pain management
Hong Chen’s lab develops noninvasive focused ultrasound intranasal delivery method
Election is one of the highest honors for contributions to health, medicine
Enzyme replacement therapy, in mice and sheep, slowed brain degeneration
Researchers from several labs to study role of transposable elements
Recognizes scientist’s contributions to Alzheimer’s disease research
Behavior surprisingly does not require brain’s visual cortex
Extended use of tofersen may help stabilize muscle strength, control
Research finds kids with prenatal exposure show more signs of psychopathology
Research uncovers how unfolded proteins are discarded, and how a perfectly good protein can wind up in the trash
Our brains consume huge amounts of energy and rely on oxygen supplied by blood vessels. When the brains of infants are deprived of oxygen for any reason, it can lead to brain injury that causes cerebral palsy, epilepsy or cognitive impairment. Song Hu, PhD, associate professor of biomedical engineering in the McKelvey School of Engineering […]
Hong Chen’s lab develops technique to generate Airy beams for ultrasound focusing
Could aid efforts to find treatments for Alzheimer’s, other diseases
‘We are all doing important work’
Epilepsy is a neurological disorder that arises from abnormal electrical activity in the brain leading to seizures. These seizure events can have a variety of causes, including genetic variants in a family of proteins that regulate potassium ions in the brain. Researchers at Washington University in St. Louis have led an international team to take […]
For animals such as mice, olfaction is their primary route to pick up social information, whether that’s identifying the dominant male in a group or figuring out the reproductive status of females. In turn, these signals can influence animals’ behavior and physiology. Pheromones in male urine, for instance, can trigger early puberty in mice. While […]
ShiNung Ching, collaborators seek to develop predictive model for secondary brain injuries
Carlos Cruchaga, PhD, a pioneer in the use of human genomic data to understand and elucidate the biology of neurodegenerative diseases such as Alzheimer’s disease, has been named an inaugural Barbara Burton and Reuben M. Morriss III Professor at Washington University School of Medicine in St. Louis. Cruchaga was installed by Chancellor Andrew D. Martin […]
The American Society of Hematology has honored John Atkinson, MD, the Samuel Grant Professor of Medicine at Washington University School of Medicine in St. Louis, for his significant contributions to the field of hematology. He is one of two recipients of the Ernest Beutler Lecture and Prize and is recognized for breakthroughs that have advanced understanding […]
Song Hu combines hardware and machine learning for precision imaging technique
WashU was first to reveal the intricate link between fragmented sleep and dementia
A new center established at Washington University School of Medicine in St. Louis aims to accelerate research into biomarkers of neurodegenerative conditions such as Huntington’s and Parkinson’s diseases, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS) and the so-called tauopathies, a group that includes Alzheimer’s disease along with rarer diseases such as frontotemporal dementia, corticobasal syndrome […]