News & Publications for:

Celeste Karch

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

Posted on December 27, 2018

Shan Jiang, Natalie Wen, Zeran Li, Umber Dube, Jorge Del Aguila, John Budde, Rita Martinez, Simon Hsu, Maria V. Fernandez, Nigel J. Cairns, Dominantly Inherited Alzheimer Network (DIAN), International FTD-Genomics Consortium (IFGC), Oscar Harari, Carlos Cruchaga & Celeste M. Karch . Translational Psychiatry, Volume 8, Issue 1, 1 December 2018, Article number 265 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Pilot Projects, Publications Faculty: , ,

CSF progranulin increases in the course of Alzheimer’s disease and is associated with sTREM2, neurodegeneration and cognitive decline

Posted on December 6, 2018

Marc Suárez‐Calvet, Anja Capell, Miguel Ángel Araque Caballero, Estrella Morenas‐Rodríguez, Katrin Fellerer, Nicolai Franzmeier, Gernot Kleinberger, Erden Eren, Yuetiva Deming, Laura Piccio, Celeste M Karch, Carlos Cruchaga, Katrina Paumier, Randall J Bateman, Anne M Fagan, John C Morris, Johannes Levin, Adrian Danek, Mathias Jucker, Colin L Masters, Martin N Rossor, John M Ringman, Leslie M Shaw, John Q Trojanowski, Michael Weiner, Michael Ewers, Christian Haass, the Dominantly Inherited Alzheimer Network, the Alzheimer’s Disease Neuroimaging Initiative. EMBO Molecular Medicine, 2018, Article number e9712 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , ,

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease

Posted on December 6, 2018

Daniel Twohig, Elena Rodriguez-Vieitez, Sigrid B. Sando, Guro Berge, Camilla Lauridsen, Ina Møller, Gøril R. Grøntvedt, Geir Bråthen, Kalicharan Patra, Guojun Bu, Tammie L. S. Benzinger, Celeste M. Karch, Anne Fagan, John C. Morris, Randall J. Bateman, Agneta Nordberg, Linda R. White, Henrietta M. Nielsen and for the Dominantly Inherited Alzheimer Network (DIAN). Acta neuropathologica communications, Volume 6, Issue 1, 26 November 2018, Page 130 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,

Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease

Posted on November 21, 2018

Iris J. Broce, […], Celeste M. Karch, Rahul S. Desikan. Acta Neuropathologica, 2018 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty:

Utility of perfusion PET measures to assess neuronal injury in Alzheimer’s disease

Posted on November 12, 2018

Nelly Joseph-Mathurin, Yi Su, Tyler M. Blazey, Mateusz Jasielec, Andrei Vlassenko, Karl Friedrichsen, Brian A. Gordon, Russ C. Hornbeck, Lisa Cash, Beau M. Ances, Thomas Veale, David M. Cash, Adam M. Brickman, Virginia Buckles, Nigel J. Cairns, Carlos Cruchaga, Alison Goate, Clifford R. Jack, Celeste Karch, William Klunk, Robert A. Koeppe, Daniel S. Marcus, Richard Mayeux, Eric McDade, James M. Noble, John Ringman, Andrew J. Saykin, Paul M. Thompson, Chengjie Xiong, John C. Morris, Randall J. Bateman and Tammie L.S. Benzinger. Alzheimer’s and Dementia: Diagnosis, Assessment and Disease Monitoring, Volume 10, 1 January 2018, Pages 669-677 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , , ,