News & Publications for:

Celeste Karch

Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer’s disease

Posted on May 22, 2019

Jonathan Vöglein, Katrina Paumier, Mathias Jucker, Oliver Preische, Eric McDade, Jason Hassenstab, Tammie L Benzinger,J ames M Noble, Sarah B Berman, Neill R Graff-Radford, Bernardino Ghetti, Martin R Farlow, Jasmeer Chhatwal, Stephen Salloway, Chengjie Xiong, Celeste M. Karch, Nigel Cairns, Hiroshi Mori,Peter R Schofield, Colin L Masters, Alison Goate, Virginia Buckles, Nick Fox, Martin Rossor,Patricio Chrem, Ricardo Allegri, John M Ringman, Günter Höglinger, Harald Steiner, Marianne Dieterich, Christian Haass, Christoph Laske, John C Morris, Randall J Bateman, Adrian Danek, Johannes Levin, Dominantly Inherited Alzheimer Network. Brain : a Journal of Neurology, Volume 142, Issue 5, 1 May 2019, Pages 1429-1440 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , ,

The BDNF Val66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease

Posted on April 1, 2019

Nicolai Franzmeier, Jinyi Ren, Alexander Damm, Gemma Monté-Rubio, Mercè Boada, Agustín Ruiz, Alfredo Ramirez, Frank Jessen, Emrah Düzel, Octavio Rodríguez Gómez, Tammie Benzinger, Alison Goate, Celeste M. Karch, Anne M. Fagan, […], John C. Morris, Randall J. Bateman & Michael Ewers. Molecular Psychiatry 2019 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , ,

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

Posted on January 31, 2019

Oliver Preische, Stephanie A. Schultz, Anja Apel, Jens Kuhle, Stephan A. Kaeser, Christian Barro, Susanne Gräber, Elke Kuder-Buletta, Christian LaFougere, Christoph Laske, Jonathan Vöglein, Johannes Levin, Colin L. Masters, Ralph Martins, Peter R. Schofield, Martin N. Rossor, Neill R. Graff-Radford, Stephen Salloway, Bernardino Ghetti, John M. Ringman, James M. Noble, Jasmeer Chhatwal, Alison M. Goate, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, Guoqiao Wang, Anne M. Fagan, Eric M. McDade, Brian A. Gordon, Mathias Jucker & Dominantly Inherited Alzheimer Network. Nature Medicine 2019 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: , , , , , , , ,

Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

Posted on January 23, 2019

Marc Suárez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, Kai Schlepckow, Miguel Ángel Araque Caballero, Nicolai Franzmeier, Anja Capell, Katrin Fellerer, Brigitte Nuscher, Erden Eren, Johannes Levin, Yuetiva Deming, Laura Piccio, Celeste M. Karch, Carlos Cruchaga, Leslie M. Shaw, John Q. Trojanowski, Michael Weiner, Michael Ewers, Christian Haass and for the Alzheimer’s Disease Neuroimaging Initiative. Molecular Neurodegeneration, Volume 14, Issue 1, 10 January 2019, Article number 1 Read More

Posted in: Axon Injury & Repair, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , ,

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

Posted on December 27, 2018

Shan Jiang, Natalie Wen, Zeran Li, Umber Dube, Jorge Del Aguila, John Budde, Rita Martinez, Simon Hsu, Maria V. Fernandez, Nigel J. Cairns, Dominantly Inherited Alzheimer Network (DIAN), International FTD-Genomics Consortium (IFGC), Oscar Harari, Carlos Cruchaga & Celeste M. Karch . Translational Psychiatry, Volume 8, Issue 1, 1 December 2018, Article number 265 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Pilot Projects, Publications Faculty: , ,