News & Publications for:

John Cirrito

An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice

Posted on June 28, 2017

Yvette I. Sheline, Tim West, Kevin Yarasheski, Robert Swarm, Mateusz S. Jasielec, Jonathan R. Fisher, Whitney D. Ficker, Ping Yan, Chengjie Xiong, Christine Frederiksen, Monica V. Grzelak, Robert Chott, Randall J. Bateman, John C. Morris, Mark A. Mintun, Jin-Moo Lee and John R. Cirrito: 2014 Sci Transl Med, 10.1126/scitranslmed.3008169 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Neurovascular Injury & Repair, Pilot Projects, Publications Faculty: , , ,

Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition

Posted on May 8, 2017

Liu, C.-C., Hu, J., Zhao, N., Wang, J., Wang, N., Cirrito, J.R., Kanekiyo, T., Holtzman, D.M., Bu, G. 2017 The Journal of neuroscience: the official journal of the Society for Neuroscience, 37 ( 15 ) pp. 4023 – 4031 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: ,

Rapid in vivo measurement of ß-amyloid reveals biphasic clearance kinetics in an Alzheimer’s mouse model

Posted on May 31, 2016

Yuede CM, Lee H, Restivo JL, et al: 2016 Journal of Experimental Medicine, 213(5), pp 677-685. Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: