Molecular Imaging of Neuroimmune responses in Degeneration (MIND)
The Chaney lab focuses on the development and evaluation of novel imaging biomarkers to investigate the inflammatory component of neurodegenerative diseases. The goals of this work are to enhance understanding, detection, and treatment of devastating neurological diseases through the development of non-invasive translational molecular imaging strategies. Specifically, we are interested in developing Positron Emission Tomography (PET) tracers targeting the innate immune system and defining the role of peripheral and central nervous system (CNS) immune responses in neurodegeneration (e.g., Alzheimer’s disease and multiple sclerosis) and infection. To achieve this, we employ multidisciplinary research at the interface of neuroscience, radiology, and immunology.
Dr. Chaney is an assistant professor at the Mallinckrodt Institute of Radiology (MIR) at Washington University in St. Louis. As a neuroimaging biologist, Dr. Chaney had extensive experience in clinical and preclinical multi-modal molecular imaging in the context of psychiatric and neurodegenerative diseases. She received a BA. Mod. in Neuroscience from Trinity College Dublin, an MRes in experimental physiology, drug discovery and Bio-imaging from Imperial College London, and a PhD in Neuroscience and Neuroimaging from the University of Manchester. Dr. Chaney was previously at Stanford University as a postdoctoral fellow and Instructor in the Department of Radiology, before joining MIR in 2022.