Marcus Raichle, MD

Marcus Raichle, MD

Alan A. and Edith L. Wolff Distinguished Professor of Medicine, WashU Radiology

Functional brain imaging with positron emission tomography and magnetic resonance

Our work uses functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) to study human brain organization and function in health and disease.

The research can be divided into two general categories: studies of normal human brain function and studies of the biological origins of functional brain imaging signals obtained with MRI and PET. We use fMRI to determine systems within the normal human brain concerned with specific cognitive and emotional functions. We are also studying patients with psychiatric diseases such as depression and anxiety to determine the system responsible for the disease and the response of these systems to treatment. We use both PET and MRI to relate changes in blood flow and brain metabolism to underlying changes in cellular activity associated with brain function.

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