Clinical and cognitive neuroscience
My research is in the fields of cognitive and clinical neuroscience. I use a range of neuroimaging, pharmacological and cognitive techniques to address two primary lines of research: The neural underpinnings of cognitive and mood dysfunction in disorders relevant to dopamine and the basal ganglia (e.g. Parkinson disease, Huntington disease, Tourette syndrome) and the effects of diabetes and obesity on the brain. I also study the natural history of structural and functional brain effects of Wolfram’s Syndrome, a neurodegenerative disease occurring in childhood and accompanied by diabetes. I am currently the scientific director of the WU Wolfram Research Clinic, and involved in both human and animal studies of the neurological effects of Wolfram Syndrome.