Tag: Marco Pignatelli

Research explores neurobiology underlying common depression symptom

Marco Pignatelli, MD, an assistant professor of psychiatry at Washington University School of Medicine in St. Louis, has received a five-year $6.5 million grant from the Wellcome Trust to unravel little-known brain functions involved in depression. His project focuses on understanding the neurobiology underlying chronic anergia, the debilitating loss of energy and enthusiasm that affects […]

Brain pathway links inflammation to loss of motivation, energy in advanced cancer

The fatigue and lack of motivation that many cancer patients experience near the end of life have been seen as the unavoidable consequences of their declining physical health and extreme weight loss. But new research from Washington University School of Medicine in St. Louis challenges that long-held assumption, showing instead that these behavioral changes stem […]