Alzheimer’s disease and frontotemporal dementia are devastating disorders that emerge following the buildup of misfolded proteins in the brain. The newest generation of Alzheimer’s therapeutics targets accumulations of the protein amyloid beta with engineered antibodies, but the results have been underwhelming, with some adverse effects, not to mention using engineered antibodies can be prohibitively expensive. […]
Scopus list of Hope Center faculty members’ publications for the week of December 1, 2024
At the Washington University in St. Louis Board of Trustees meeting March 1, numerous faculty members were appointed with tenure, promoted with tenure or granted tenure. Their new roles and titles take effect July 1, unless otherwise indicated. Appointment with tenure Steven Miles as a professor of history in Arts & Sciences. Granting of tenure Paul […]
Scopus list of publications for September 10, 2023
Funding from the National Institutes of Health will help Jackrel and her team study Matrin-3, a poorly understood protein linked to several neurodegenerative disorders.
Anuradhika Puri, PhD, a postdoctoral research associate working with Meredith Jackrel, PhD in the Department of Chemistry in Arts & Sciences at Washington University in St. Louis, won the Amyotrophic Lateral Sclerosis Association’s Milton Safenowitz Postdoctoral Fellowship. The $150,000 award supports her work on applying the human disaggregase, HtrA1, to counter amyotrophic lateral sclerosis, or ALS. Originally published on […]
Scopus list of Hope Center faculty members’ publications for the week of August 21, 2022
Jai Rudra, Meredith Jackrel to use nanofibers to develop new vaccines
Scopus list of Hope Center faculty members’ publications for the week of June 18, 2021
Three-year $136,560 National Research Service Award