Scopus list of Hope Center faculty members publications for the week of June 2, 2024
Tag: Rohit Pappu
Hope Center Member Publications: April 14, 2024
![](https://hopecenter.wustl.edu/files/2021/06/publications-350x176.png)
Scopus list of publications for the week of April 14, 2024
WashU engineers manage a first: measuring pH in cell condensates
![](https://hopecenter.wustl.edu/files/2024/04/3-18-2024_WashU-engineers-manage-a-first-measuring-pH-in-cell-condensates-fd767a1f5e4364a6-350x243.png)
Scientists trying to understand the physical and chemical properties that govern biomolecular condensates now have a crucial way to measure pH and other emergent properties of these enigmatic, albeit important cellular compartments. Condensates are communities of proteins and nucleic acids. They lack a membrane and come together and fall apart as needed. The nucleolus is […]
Timing matters: Condensates’ composition determined by when RNA is added
![](https://hopecenter.wustl.edu/files/2023/12/12-4-2023Timing-matters-Condensates-composition-determined-by-when-RNA-is-added-350x215.png)
Rohit Pappu, collaborators from Duke University make discovery with model fungus
RNA’s solo act on the ever-changing stage of cellular dynamics
![](https://hopecenter.wustl.edu/files/2023/11/11-20-2023_RNAs-solo-act-on-the-ever-changing-stage-of-cellular-dynamics-350x233.jpg)
Rohit Pappu, collaborators find networking afforded by interactions among RNA molecules can enable different phase behavior when heating or cooling
Mapping the cell’s membrane-less compartments
![](https://hopecenter.wustl.edu/files/2023/11/11-1-2023_Mapping-the-cells-membrane-less-compartments-350x233.jpg)
WashU and St. Jude groups uncover the rules for organization of cellular condensates implicated in ALS
Pappu installed as Gene K. Beare Distinguished Professor of Biomedical Engineering
![](https://hopecenter.wustl.edu/files/2023/10/10-25-2023_Pappu-installed-as-Gene-K.-Beare-Distinguished-Professor-of-Biomedical-Engineering-350x233.jpg)
Rohit V. Pappu, PhD, an internationally renowned researcher in biomolecular condensates and intrinsically disordered proteins, was installed Oct. 9 as the Gene K. Beare Distinguished Professor of Biomedical Engineering at Washington University in St. Louis. Pappu is a professor of biomedical engineering and director of the Center for Biomolecular Condensates at the McKelvey School of […]
Hope Center Member Publications: September 17, 2023
Scopus list of publications for September 17, 2023
Pappu to explore ways in which charge contributes to diverse states of proteins
![](https://hopecenter.wustl.edu/files/2023/05/5-12-2023_Pappu-to-explore-ways-in-which-charge-contributes-to-diverse-states-of-proteins-350x233.jpg)
Intrinsically disordered proteins (IDPs) are defined by structural diversity, and the determinants of this diversity are an important area of biophysical investigation. IDPs are involved in a range of important biological processes, including cell signaling and regulation, that allow healthy cells to respond to environmental factors appropriately, but they are also associated with human diseases […]
Interfaces play important role in condensate behavior
![](https://hopecenter.wustl.edu/files/2023/01/1-23-2023_Interfaces-play-important-role-in-condensate-behavior-350x243.png)
Research from labs of Rohit Pappu, collaborators sheds light on condensate characteristics
Center for Biomolecular Condensates launches
![](https://hopecenter.wustl.edu/files/2022/11/11-7-2022_Center-for-Biomolecular-Condensates-launches-350x233.jpg)
Symposium brings together key leaders in the field
How do cells take out the trash?
![](https://hopecenter.wustl.edu/files/2022/09/9-12-2022_How-do-cells-take-out-the-trash-350x233.jpg)
Research uncovers how unfolded proteins are discarded, and how a perfectly good protein can wind up in the trash
Hope Center Member Publications
![](https://hopecenter.wustl.edu/files/2021/06/publications-350x176.png)
Scopus list of publications for September 4, 2022
New structure found in cells
![](https://hopecenter.wustl.edu/files/2022/07/7-15-2022_New-structure-found-in-cells-350x233.jpg)
Every cell contains millions of protein molecules. Some of them have the ability to phase-separate to form non-membrane-bound compartments, called biomolecular condensates, inside a cell. It has long been assumed that there was no further structure underlying these condensates, only solution-soluble proteins. A research group led by Rohit Pappu, PhD, the Gene K. Beare Distinguished Professor […]
Pappu lab untangles more IDR secrets
![](https://hopecenter.wustl.edu/files/2021/08/Pappu-News-350x196.png)
Intrinsically disordered regions (IDRs) of proteins, when tethered to folded domains, function either as flexible tails or as linkers between domains. Most IDRs are composed of a mixture of oppositely charged residues. Recent measurements of tethered polyampholytes have shown that arginine- and lysine-rich sequences tend to behave very differently from one another. In a paper […]
Understanding features that help cells stay organized
![](https://hopecenter.wustl.edu/files/2021/08/Pappu-News-350x196.png)
Longstanding collaboration leads to new findings about processes associated with neurodegenerative diseases
International team finds new mechanism critical for formation of membrane vesicles
![](https://hopecenter.wustl.edu/files/2021/08/Pappu-News-350x196.png)
These vesicles are critical for proper cell function
Hope Center member publications
![](https://hopecenter.wustl.edu/files/2021/06/publications-350x176.png)
List of publications for the week of November 8, 2021
NIH awards $3.1 million grant for Washington University, St. Jude ALS research
![](https://hopecenter.wustl.edu/files/2021/08/Pappu-News-350x196.png)
NIH awards $3.1 million grant for Washington University, St. Jude ALS research