About
The Hope Center Program on Protein Aggregation and Neurodegeneration (HPAN) is one of five Interdisciplinary Research Centers (IRCs) selected by the Dean of Washington University School of Medicine. As a BioMed 21 IRC, HPAN was awarded support from the Dean, and space in the new BJC Institute of Health (BJC-IH).
Below are those HPAN labs that are based in the BJC-IH. For the complete list of HPAN labs, click here.
Carlos Cruchaga Lab
Next-gen sequencing technology to identify genetic variants implicated in neurodegeneration
Anne Fagan Lab
Cerebrospinal fluid and plasma biomarkers of early-stage Alzheimer’s disease
Alison Goate Lab
Linkage and associated studies to uncover genetic susceptibility to neuropsychiatric disease
Henry Han Lab
Imaging and functional studies of cerebral vessels associated with neurovascular disease
David Holtzman Lab
Cellular/Molecular/Biomarker studies of Alzheimer’s disease and neonatal brain injury
Jin-Moo Lee Lab
Amyloid plaque pathogenesis
Erik Musiek Lab
Aging, oxidative stress, and circadian clock genes in neurodegenerative diseases.
Richard Perrin Lab
Novel cerebrospinal fluid biomarkers for early diagnosis, prognosis, and staging of neurodegenerative diseases.
Greg Zipfel Lab
Role of amyloid-ß peptide and cerebral amyloid angiopathy in neurovascular dysfunction, ischemic brain injury and subarachnoid hemorrhage
