Greg Zipfel Lab

Role of amyloid-ß peptide and cerebral amyloid angiopathy in neurovascular dysfunction, ischemic brain injury and subarachnoid hemorrhage
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Research Overview

The Cerebrovascular Research Laboratory has two main interests: 1) Examining the pathophysiologic effects of amyloid-ß peptide on cerebral arteriolar function, and determining the manner and extent to which such effects contribute to diseases such as ischemic brain injury, cerebral amyloid angiopathy, and Alzheimer’s Disease; and 2) Exploring the molecular basis and therapeutic intervention for vasospasm and cognitive deficits following experimental aneurysmal subarachnoid hemorrhage.

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