Study pegs certain cellular activities to driving Alzheimer’s disease
Category: Lysosome
The brain has a waste removal system and scientists are figuring out how it works
The brain needs to flush out waste products to stay healthy and fend off conditions like Alzheimer’s disease. Scientists are beginning to understand how the the brain’s waste removal system works. [Transcript] A MARTÍNEZ, HOST: Turns out the brain needs regular cleaning. Otherwise, it gets clogged up with waste products, including some associated with diseases […]
Diwan named inaugural Shaeffer professor
Abhinav Diwan, MD, a highly regarded cardiologist with expertise in the molecular underpinnings of cardiovascular disease, has been named the inaugural Charlie W. Shaeffer, MD, Professor of Cardiology at Washington University School of Medicine in St. Louis. Diwan was installed by David H. Perlmutter, MD, executive vice chancellor for medical affairs, the George and Carol […]
How do toxic proteins accumulate in Alzheimer’s and other diseases?
Key steps leading to such accumulation identified; could inform new therapeutic approaches
Cooper receives two NIH grants to study rare genetic disease
Jonathan D. Cooper, PhD, a professor of pediatrics, of genetics and of neurology at the Washington University School of Medicine in St. Louis, received two grants totaling $2.55 million over five years from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health (NIH). Cooper will study enzyme replacement therapy as a possible […]
Rejuvenated immune cells can improve clearance of toxic waste from brain
Findings in mice suggest new therapeutic approach to Alzheimer’s, other age-related diseases
Research offers clues for treating fatal neurological disorder in kids
Enzyme replacement therapy, in mice and sheep, slowed brain degeneration
$9 million to fund study of ‘jumping genes’ in Alzheimer’s
Researchers from several labs to study role of transposable elements
Cruchaga awarded Zenith Fellowship Award
Recognizes scientist’s contributions to Alzheimer’s disease research
Risk, resiliency in aging brain focus of $33 million grant
Multicenter team aims to understand how, why brain changes with age
Diabetes, metabolic syndrome in mice treated with novel class of compounds
Improves insulin secretion, lowers blood sugar
New Alzheimer’s treatment targets identified
Study points to FDA-approved drugs that have potential to slow or reverse brain damage
Lee named head of Department of Neurology
Recognized for expertise in brain injury, impact as mentor
Board grants faculty appointments, promotions, tenure
At the Washington University in St. Louis Board of Trustees meeting May 7, numerous faculty members were appointed or promoted with tenure or granted tenure, effective July 1 unless otherwise indicated. Promotion with tenure Megan Tierney Baldridge, MD, PhD, to associate professor of medicine at the School of Medicine; Trevor G. Gardner II to professor of […]
Studies reveal skull as unexpected source of brain immunity
Immune cells from skull bone marrow guard the brain, spinal cord
WashU, Pitt awarded $10.7 million for Alzheimer’s disease research
Study to look for genetic pathways that lead to formation of plaques, tangles
Team developing tool to handle big data generated by advanced imaging tool
Washington University collaboration aims to advance 3D imaging of living cells, tissues
Draining brain’s debris enhances Alzheimer’s therapies in mice
Impaired drainage also may play a role in Alzheimer’s in people