Meeting Archives

Lipid Metabolism Group

2024 Spring/Summer Schedule

January 12, 2024: Birol Cabukusta (Leiden University, The Netherlands) “A Genetic Toolbox to Study Intracellular Lipid Trafficking”
February 9, 2024: Paola Gamba (University of Turin, Italy) “Brain cholesterol dysmetabolism: A key feature in Alzheimer’s disease”
March 8, 2024: Rik van der Kant (Vrije Universiteit Amsterdam) “Cholesterol dyshomeostasis as a driver of Alzheimer’s Disease”
April 12, 2024: Irina Pikuleva (Case Western Reserve University) “Pharmacologic CYP46A1 activation by low dose anti-HIV drug efavirenz: From purified enzyme to mice and humans”
May 10, 2024: Michael Strickland (Randolph lab, WashU Pathology & Immunology) “ApoE Registry Impacts Binding of ApoE to its Receptors”
June 14, 2024: Andrew Roth (Philips lab, WashU Medicine) “Beyond Metabolism: Understanding the Role of Cholesterol Oxidation in Tuberculosis”
July 12, 2024: Yuqing Zhu (Skeath lab, WashU Genetics) “Loss of dihydroceramide desaturase drives neurodegeneration by disrupting endoplasmic reticulum and lipid droplet homeostasis in glial cells”

2023 Schedule

February 10, 2023: Lance Johnson (University of Kentucky) “APOE, immunometabolism, and lipid droplet dynamics”
March 10, 2023: Danira Toral (Paul/Cashikar lab, WashU Psychiatry) “Oxysterol control of neuroinflammation and neurodegeneration”
April 14, 2023: Tiago Gil Oliveira (University of Minho) “The role of the phospholipase D pathway in hippocampal functioning and Alzheimer’s disease”
May 12, 2023: Hongjun (Harry) Fu (The Ohio State University) “Lipid Dyshomeostasis in Frontotemporal Dementia”
June 9, 2023: Jiyeon Lee (Musiek lab, WashU Neurology) “Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy”
July 14, 2023: Yun Chen (Holtzman lab, WashU Neurology) “APOE3ch influences the microglial response to Aβ plaques which suppresses Aβ-induced tau seeding and spreading”
August 11, 2023: Travis Tabor (Holtzman lab, WashU Neurology) “Elucidating roles of microglial lipid droplets in neurodegeneration”
September 8, 2023: Priyanka Narayan (NIH/NIDDK) “Understanding the effects of APOE isoforms on glial lipid metabolism”
November 10, 2023: Matheus Victor (Massachusetts Institute of Technology) “Human Microglial State Dynamics in Alzheimer’s Disease Progression”

2022 Schedule

January 14, 2022: Gwendalyn Randolph (WashU Pathology & Immunology) – WiP, JC “Macrophage membrane cholesterol and lipidome in inflammation and host defense”
February 11, 2022: Michael Strickland (Holtzman lab, WashU Neurology) – WiP “ApoE-Trem2 Axis Impacts Cholesterol Metabolism”
March 11, 2022: Victoria Ismail (Kast lab, WashU Cell Biology & Physiology) – WiP “The GTPase activity of DFCP1 modulates lipid droplet metabolism”
April 8, 2022: Clay Semenkovich (WashU Medicine) – WiP “Palmitoylation Cycling and Metabolic Disease”
May 13, 2022: Yun Chen (Holtzman lab, WashU Neurology) – WiP “Preliminary characterization of the impacts of ApoE3 Christchurch mutation on lipid metabolism and pathology for Alzheimer’s Disease”
June 10, 2022: Pallavi Chandra (Philips lab, WashU Medicine) “Host-pathogen lipid metabolism during Mycobacterium tuberculosis infection”
July 8, 2022: Nada Abumrad (WashU Medicine) “Fatty Acids and Cognition”
September 9, 2022: Irfan Lodhi (WashU Medicine) “Peroxisome-Mitochondria Crosstalk Regulating Energy Homeostasis”
November 11, 2022: David Ford (Saint Louis University) “Roles for Plasmalogens and Chlorolipids in Inflammation”
December 9, 2022: Alexandra Litvinchuk (Holtzman lab, WashU Neurology) “The role of ApoE4 in lipid dysregulation in glia in tauopathy and Alzheimer’s disease”