Monday Noon Seminars

Talks organized around themes of shared biological mechanisms, neurobiology, and therapeutics Read More


Monday Noon seminars are hosted by the Hope Center and the Department of Neurology.  Talks are organized around mini-series topics; each mini-series is organized by Hope Center faculty members to feature investigators from Washington University as well as one outside speaker. Monday Noon seminars run from September through May each year.

All seminars are listed on the Neuroscience Calendar of the Office of Neuroscience Research.

For inquiries, contact John Cirrito or Cindy Lawrence.

2015/2016 Schedule

Mondays, 12-1p
November – June
Holden Auditorium (Farrell Learning and Teaching Center)

Mini-Series Topics:

Mechanisms of Muscle Weakness
Stem Cell Therapeutics
Epigenetic Modifications in Aging and Disease
Diabetes and the Brain
Transcriptional and epigenetic control of neural development

Special Hope Center/Ophthalmology/Neurology Seminars
Special Seminar: Cheryl Lichti (University of Texas Medical Branch)
Special Seminar: Winners, Hope Center Awards

Mechanisms of Muscle Weakness

Organizer, Chris Weihl

  • November 2: Dongsheng Duan (University of Missouri), “Dystrophin-based DMD gene therapy: from mice to dogs”
  • November 9: Alfred Goldberg (Harvard University), “Molecular Mechanisms of Muscle Atrophy and Cancer Cachexia”
  • November 30: Chris Weihl (WUSTL Neurology), “Protein quality control in inherited and acquired myopathies”
  • December 7: Christina Gurnett (WUSTL Neurology), “Hypotonia and contractures: lessons from genetic studies of scoliosis and arthrogyprosis”

Stem Cell Therapeutics

Organizer, Hope Center NeuroRestorative Therapy Group

  • January 4: Shelly Sakiyama-Elbert (WUSTL Biomedical Engineering), “Materials for Cell Transplantation After Spinal Cord Injury”
  • January 11: Nicholas Maragakis (Johns Hopkins University School of Medicine), “Stem Cell Transplantation as a Neuroprotective Strategy for Treating Amyotrophic Lateral Sclerosis”
  • January 25: Fumihiko Urano (WUSTL Internal Medicine), “A Soluble Endoplasmic Reticulum Factor-Based Regenerative Therapy for Diabetes and Neurodegeneration in Wolfram Syndrome”
  • February 1: Andrew Yoo (WUSTL Developmental Biology), “Subtype-specific Neuronal Conversion of Human Fibroblasts and Disease Modeling”

Epigenetic Modifications in Aging and Disease

Organizer, Valeria Cavalli

  • February 8: Valeria Cavalli (WUSTL Neuroscience), “Epigenetic modifications promoting axon regeneration”
  • February 22: Hiroko Yano (WUSTL Neurosurgery), “Manipulating epigenetic mechanisms to save Huntington’s disease neurons”
  • February 29: Ting Wang (WUSTL Genetics), “Transposable elements and epigenome evolution”
  • March 7: Michael Kobor (University of British Columbia), “Epigenetic Signatures of Human Aging”

Diabetes and the Brain

Organizer, Tamara Hershey and Shannon Macauley-Rambach

  • March 21: Tamara Hershey (WUSTL Psychiatry), Shannon Macauley-Rambach (WUSTL Neurology), “Diabetes and the Brain – from mice to humans”
  • March 28: Maria Remedi (WUSTL Internal Medicine), “The role of KATP channels in Diabetes and Brain Pathologies”
  • April 4: Suzanne Craft (Wake Forest Baptist Medical Center), “Insulin and Alzheimer’s Disease: The Path of Most Resistance”
  • April 11: Ana Maria Arbelaez (WUSTL Pediatrics), “Brain Hormone Interaction in Hypoglycemic Counterregulation”

Transcriptional and epigenetic control of neural development

Organizers, Kelly Monk and Andrew Yoo (co-hosted with the Department of Developmental Biology)

  • April 25: Gail Mandel (Oregon Health & Science University), “New Insights into the Dysfunctional Circuitry Underlying Rett Syndrome”
  • May 2: Azad Bonni (WUSTL Neuroscience), “Epigenetic regulation of neuronal connectivity in the brain”
  • May 9: Harrison Gabel (WUSTL Neuroscience),  “The neuron-specific epigenome in development and disease”
  • May 16: Kristen Kroll (WUSTL Developmental Biology), “Gene regulatory networks in neural development and disease”

Special Hope Center/Ophthalmology/Neurology Seminars

  • Wednesday, September 30: Chad Dickey (University of South Florida), “Drowsy chaperones: How the protein quality control system enables diseases of aging”
    12:00 PM
    Location: Erlanger Auditorium (Medical Campus)
  • Thursday, October 15: Monica Vetter (University of Utah), “Birth and death in the retina: pathways modulating proliferation, differentiation and neurodegeneration”
    4:00 PM
    Location: Cori Auditorium (Medical Campus)
  • Monday, October 26: Erika Holzbaur (University of Pennsylvania School of Medicine), “Autophagy and mitophagy in neuronal homeostasis and neurodegeneration”
    12:00 PM
    Location: Cori Auditorium (Medical Campus)

Special Seminar

  • December 14: Cheryl Lichti (University of Texas Medical Branch), “A Proteomic Survey of Glioma Stem Cells”

Special Seminar: Winners, Hope Center Awards

  • June 6: Cheryl Leyns (Holtzman Lab, WUSTL Neurology), “Direct delivery of full-length, therapeutic anti-tau antibodies to the brain by gene transfer”
    Lauren Walker (DiAntonio Lab, WUSTL Developmental Biology),  
    “MAPK signaling functions upstream of SARM1 to promote axonal degeneration”

Past Mini-Series Topics

Mini-series topics from previous seasons.

Previous mini-series