Monday Noon Seminars

Talks organized around themes of shared biological mechanisms, neurobiology, and therapeutics Read More


Monday Noon seminars are hosted by the Hope Center and the Department of Neurology.  Talks are organized around mini-series topics; each mini-series is organized by Hope Center faculty members to feature investigators from Washington University as well as one outside speaker. Monday Noon seminars run during the academic year, typically September through May.

All seminars are listed on the Office of Neuroscience Research (ONR) Calendar.

For inquiries, contact John Cirrito or Cindy Lawrence.

2018/2019 Schedule

Mondays, 12-1p
September – June
Holden Auditorium (Farrell Learning and Teaching Center)

Mini-Series Topics:

Translational Machinery and Neurological Diseases
Sleep and Disease
Environmental Factors in Disease
Stroke, Plasticity and Recovery
Cholesterol Metabolism in Disease
Modeling Neurological Disorders Using Stem Cell-based Approaches

Special Hope Center Seminars

Translational Machinery and Neurological Diseases

Organizer, Joseph Dougherty

  • September 24: Eric Wang (University of Florida) “The double life of RNA binding proteins in muscle and the central nervous system – implications for Myotonic Dystrophy”
  • October 1: Sebla Kutluay (WashU Molecular Microbiology) “Unexpected Roles of RNA-binding Proteins in HIV-1 Replication”
  • October 8: Brian Clark (WashU Ophthalmology & Visual Sciences) “Comprehensive Analysis of Retinal Development at single-cell resolution”
  • October 15: Sergej Djuranovic (WashU Cell Biology & Physiology) “mRNA sequence determinants of the efficient protein synthesis”

Sleep and Disease

Organizer, Yo-El Ju

  • November 19: Amy Licis (WashU Neurology) “Sleep disturbances in Wolfram syndrome”  
  • November 26: Erik Herzog (WashU Biology) “Clock cartography: Mapping circadian connections and dysfunctions”
  • December 3: Yo-El Ju (WashU Neurology) “Sleep and amyloid-beta”
  • December 10: Jon Willie (Emory University) “Deep Brain Stimulation: Hope for Narcolepsy with Cataplexy?”

Environmental Factors in Disease

Organizer, Ream Al-Hasani

  • January 7: Brad Racette (WashU Neurology) “Human Environmental Mn Exposure as a Model of Neurodegeneration”
  • January 14: Joseph Bloom (WashU Psychiatry) “Genetic and environmental factors influencing nicotine metabolism and dependence”
  • CANCELLED January 28: Jordan McCall (WashU Anesthesiology) “The maternal and homecage environments as important drivers of neural circuit dysfunction”
  • February 4: Patricia Jensen (NIH/National Institute of Environmental Health Sciences) “Genetic approaches toward defining noradrenergic neuron diversity”

Stroke, Plasticity and Recovery

Organizer, Jin-Moo Lee

  • February 18: Jin-Moo Lee (WashU Neurology) “Plasticizing the Cortex to Enhance Stroke Recovery”
  • February 25: Gregory Zipfel (WashU Neurosurgery) “The Promise of Conditioning-Based Therapy for Aneurysmal Subarachnoid Hemorrhage”
  • March 4: S. Thomas Carmichael (University of California, Los Angeles) “Neural Repair after Stroke: Smart Mice to Smart Humans”
  • March 11: Nico Dosenbach (WashU Neurology) “Precision Functional Mapping of Individual Brains”

Cholesterol Metabolism in Disease

Organizers, Anil Cashikar, Steve Mennerick

  • March 25: Gwendalyn Randolph (WashU Pathology & Immunology) “Lipoprotein trafficking through the interstitium and lymphatics in chronic inflammatory disease”
  • April 1: Suzanne Pfeffer (Stanford University) “Cholesterol and membrane trafficking: implications for Niemann Pick Type C and familial Parkinson’s disease”
  • April 8: Douglas Covey (WashU Developmental Biology) “Click chemistry for studies of cholesterol, oxysterol and neurosteroid biology”
  • April 15: Jonathan Cooper (WashU Pediatrics) “The same, but different. New lessons about Batten disease”

Modeling Neurological Disorders Using Stem Cell-based Approaches

Organizers, Andrew Yoo, Samantha Morris, Celeste Karch

  • April 22: Aaron DiAntonio (WashU Developmental Biology) “Axon Degeneration: Mechanistic Insights Yield New Therapeutic Strategies for Neurodegenerative Diseases”
  • April 29: Albert Kim (WashU Neurosurgery) “Maintenance and modeling of glioblastoma stem-like cells”
  • May 13: Celeste Karch (WashU Psychiatry) “Modeling tauoapthies in human stem cells”
  • May 20: Justin Ichida (University of Southern California) “Using Cellular Reprogramming to Identify New Therapeutic Targets for Neurodegenerative Diseases”

Special Seminars

  • October 22: Ronald Cohn (Fluidigm), Stephen Oh (WashU Medicine) “Hyperion Imaging System”
  • November 12: Leonard Petrucelli (Mayo Clinic) “Mechanistic and Therapeutic Insights into c9orf72 FTD/ALS”
    *BJC Investigator Program Seminar co-hosted by the Department of Neurology and Department of Neuroscience
  • March 1: Heather Rice (KU Leuven, Belgium) “A novel role for Alzheimer’s Amyloid Precursor Protein in GABAergic signaling”
  • March 18: State of the Hope Center
    • Hiroko Yano (WashU Neurosurgery) “The role of DNA methylation in Huntington’s disease”
    • Celeste Karch (WashU Psychiatry)“Neuronal subtype-specific vulnerability in tauopathies using human stem cells”
  • June 10: Winners, Hope Center Awards – NOTE This seminar will be held in BJC Institute of Health 9AB.

    • Andrew Findlay (Weihl Lab, Neurology)
      “Therapeutic modulation of chaperone functions in LGMD1D”
    • Zachary Rosenthal (Lee Lab, Neurology)
      “Local perturbations in cortical excitability propagate differentially through large-scale functional networks”

Suggest Mini-Series Topics

Please keep in mind:

  • Anyone (PI or lab member) can suggest topics.
  • Each mini-series typically includes three speakers from Washington University, and one outside investigator.
  • You do not have to suggest particular WashU or outside speakers but, if you have suggestions, please include.

Submit mini-series topic(s)

Past Mini-Series Topics

Mini-series topics from previous seasons.

Previous mini-series