Clocks & Sleep

Organizers: Erik Herzog, Paul Taghert, and Dmitri Nusinow Read More


The Hope Center is pleased to announce that Clocks & Sleep Club now is the Hope Center Clocks & Sleep Club.  This affiliation reflects an expansion of the existing group, aimed to help promote ongoing research on the role of sleep and circadian rhythms in neurodegenerative disease.   The founders and organizers, Erik Herzog and Paul Taghert, will continue in their roles as the group meets monthly to discuss recent advances in the study of biological timing and sleep.

Labs working on biological rhythms include:

Erik Herzog. Molecules, cells and circuits of mammalian circadian timing.

Paul Taghert. Molecules, cells and circuits of insect circadian timing.

Dmitri Nusinow. Circadian regulation of physiology and development in plants.

David Holtzman. The role of normal and disrupted daily rhythms in amyloid beta production and Alzheimer’s Disease progression and therapies.

Michael Hughes. Daily regulation of gene expression.

Shin-Ichiro Imai. Epigenetics of circadian timing and aging.

Yo-El Ju. Sleep and neurological diseases.

Daniel Kerschensteiner. Neural circuits controlling circadian rhythms and sleep.

István Kiss. Coupled oscillator behavior in biological and electrochemical systems.

Brendan Lucey. Sleep and Alzheimer’s disease.

Erik Musiek. The role of clock genes and circadian rhythms in neurodegeneration.

Jeanne Nerbonne. Circadian regulation of excitability and channel biology.

Joshua Rubin. Chronotherapy for brain cancer.

Paul Shaw. Genetics and benefits of sleep.

Students can sign up for and participate in Clocksclub for 1 credit at WashU.

Organizers/Contact Information

For additional information about the Clocks & Sleep Club, please contact the faculty organizers Erik Herzog, Dmitri Nusinow or Paul Taghert, or our administrative coordinator, Jan Konrad.

2019/2020 Schedule, Clocks & Sleep Club

1st Friday of the month
BJC Institute of Health 9AB (unless otherwise noted)

NOTE: Presenters have 30 minutes for slides and 15 minutes for questions.

  • September 6: Jeffrey Haspel (WashU Medicine)“Circadian signatures in chronic lung disease”, Chi-Chan Lee (Kerschensteiner lab, WashU Ophthalmology & Visual Sciences) “Organization and functions of the intergeniculate leaflet”
  • October 4: Celia McKee (Musiek lab, WashU Dept. of Neurology) “An Update of Circadian Modulation of Protein Degradation”, Dmitri Nusinow (Donald Danforth Plant Science Center) “Protein interactions within the plant circadian clock”
  • October 16*: Boris Kotchoubey (University of Tübingen) “Sleep in disorders of consciousness”
    *NOTE special seminar: 2:00pm in Farrell LTC 304
  • November 1: Geraldine Kress (WashU Neurology) “Circadian Modulation of Hippocampal Function during Alzheimer’s Disease Pathogenesis”, Paul Taghert (WashU Dept. of Neuroscience) “Hub-organized parallel circuits of central circadian pacemaker neurons for visual photoentrainment in Drosophila”
  • December 6: Farshid Guilak (WashU Orthopaedic Surgery) “Designer stem cells for synthetic (chrono)biology: A joint venture”, Chanung Wang (Holtzman lab, WashU Neurology) “‘Identifying interactions between Sleep, APOE genotype, and Neuritic plaque tau pathology”
  • January 10*: Jeff Jones (Herzog lab, WashU Biology) “Circadian circuits underlying daily rhythms in corticosterone release”, Qianli Wang (Colonna lab, WashU Pathology & Immunology) “The roles of REV-ERBα and circadian rhythm in intestinal type 3 innate lymphoid cells”
    *NOTE date
  • January 31*: Thomas Jones, Darrell Moore (East Tennessee State)
    Thomas Jones:
    “To feed or not to feed: chronoecology of aggression in spiders”
    Darrell Moore: “Chronoecology: how the honey bee time memory functions within the ephemeral environment”
    *NOTE special seminar: 3:30 in BJC-IH 9AB
  • February 7: Fang Gao (Chen lab, WashU Anesthesiology) “Neural circuit of contagious itch: an update”, Eric Landsness (Lee lab, WashU Neurology) “Local slow wave sleep and stroke”
  • March 6: Anna Damato (Herzog lab, WashU Biology) “Circadian rhythms in glioblastoma tumors and effects of timed chemotherapy”, Michael Fitzpatrick (Kerschensteiner lab, WashU Ophthalmology & Visual Sciences) “Homeostatic Plasticity in Retinal Illuminance-Detection Circuits”
  • CANCELLED – April 3: Chao Zhou (WashU Biomedical Engineering), Musiek lab (WashU Neurology)
  • POSTPONED – April 10*: Ketema Paul (University of California, Los Angeles)
    *NOTE special seminar: 3:30pm in Holden Auditorium
  • CANCELLED – April 24*: Erin Gibson (Stanford University) “Circadian modulation of oligodendroglial lineage cells and myelination in development and disease”
    *NOTE special seminar: 4:00pm in BJC-IH 9AB
  • May 1: Holtzman lab (WashU Neurology), Nusinow lab (Donald Danforth Plant Science Center)

All meetings are listed on the Office of Neuroscience Research (ONR) Calendar.

Archives of previous seasons





Spring 2015

Clocks & Sleep Club Faculty

Faculty organizers: Erik Herzog, Paul Taghert, Dmitri Nusinow

Affiliated Faculty

Ryan Bogdan (WashU Psychological & Brain Sciences)
Thomas Burris (St. Louis College of Pharmacy/WashU Anesthesiology)
Yao Chen (WashU Dept. of Neuroscience)
Meaghan Creed (WashU Anesthesiology)
Erik Herzog (WashU Biology)
David Holtzman (WashU Neurology)
Michael Hughes (WashU Medicine)
Shin-Ichiro Imai (WashU Developmental Biology)
Yo-El Ju (WashU Neurology)
Daniel Kerschensteiner (WashU Ophthalmology & Visual Sciences)
István Kiss (SLU Chemistry)
Geraldine Kress (WashU Neurology)
Brendan Lucey (WashU Neurology)
Erik Musiek (WashU Neurology)
Jeanne Nerbonne (WashU Medicine)
Aaron Norris (WashU Anesthesiology)
Dmitri Nusinow (Donald Danforth Plant Science Center)
Thomas Papouin (WashU Dept. of Neuroscience)
Joshua Rubin (WashU Pediatrics)
Paul Shaw (WashU Dept. of Neuroscience)
Paul Taghert (WashU Dept. of Neuroscience)
Kelvin Yamada (WashU Neurology)
Chao Zhou (WashU Biomedical Engineering)

Archive of previous Clocks & Sleep Club meetings