Clocks & Sleep

Organizers: Erik Herzog, Paul Taghert, and Michael Hughes Read More


The Hope Center is pleased to announce that Clocks & Sleep Club now is the Hope Center Clocks & Sleep Club.  This new affiliation reflects an expansion of the existing group, aimed to help promote ongoing research on the role of sleep and circadian rhythms in neurodegenerative disease.   The founders and organizers, Erik Herzog and Paul Taghert, will continue in their roles as the group meets monthly to discuss recent advances in the study of biological timing and sleep.

Labs working on biological rhythms include:

Erik Herzog. Molecules, cells and circuits of mammalian circadian timing.

Paul Taghert. Molecules, cells and circuits of insect circadian timing.

Dmitri Nusinow. Circadian regulation of physiology and development in plants.

David Holtzman. The role of normal and disrupted daily rhythms in amyloid beta production and Alzheimer’s Disease progression and therapies.

Michael Hughes. Daily regulation of gene expression.

Shin-Ichiro Imai. Epigenetics of circadian timing and aging.

Yo-El Ju. Sleep and neurological diseases.

István Kiss. Coupled oscillator behavior in biological and electrochemical systems.

Brendan Lucey. Sleep and Alzheimer’s disease.

Erik Musiek. The role of clock genes and circadian rhythms in neurodegeneration.

Jeanne Nerbonne. Circadian regulation of excitability and channel biology.

Joshua Rubin. Chronotherapy for brain cancer.

Paul Shaw. Genetics and benefits of sleep.

Students can sign up for and participate in Clocksclub for 1 credit at WashU.

Organizers/Contact Information

For additional information about the Clocks & Sleep Club, please contact the organizers Erik Herzog, Michael Hughes or Paul Taghert, or our administrative coordinator, Jan Konrad.

2017/2018 Schedule, Clocks & Sleep Club

1st Friday of the month
BJC Institute of Health 9AB (unless otherwise noted)

  • July 7: Michael Hughes (WashU Medicine) “Guidelines for Genome-Scale Analyses of Circadian Rhythms: Emphasis on Studies of Mammalian Brains”, Dmitri Nusinow (Danforth Plant Science Center) Hybrid data/journal club
  • August 11*: Christy Hoffmann (Hughes Lab, WashU Medicine) , Paul Taghert (WashU Dept. of Neuroscience)“Melanopsin-Encoded Response Properties of Intrinsically Photosensitive Retinal Ganglion Cells”  and “Direct Midbrain Dopamine Input to the Suprachiasmatic Nucleus Accelerates Circadian Entrainment”
    *rescheduled from August 4
  • September 1: Jeff Jones (Herzog Lab, WashU Biology) “In vivo circadian rhythms and light responses of VIPergic neurons of the suprachiasmatic nucleus”, Jake Hughey (Vanderbilt University) “Machine learning around the clock”
  • October 6: Brian Lananna (Musiek Lab, WashU Neurology) “Cell-autonomous regulation of astrocyte activation by the circadian clock protein BMAL1”JiaJia Li (Hughes Lab, WashU Medicine) “Achilles (Achl) is a circadian clock controlled gene that regulates the immune function and its rhythmicity in Drosophila”
  • November 3: Xitong Liang (Taghert Lab, WashU Dept. of Neuroscience) “Rhythms outside the clock”, Andy Liu (University of Memphis) “Circadian Clocks and Cell Physiology: Circle of Life” 
  • December 1: Silke Meiners (Ludwig-Maximilians-University, Muinch), Ron Anafi (University of Pennsylvania)
  • January 12 in BJCIH 7AB*: Sonya Bahar (UMSL) “Time is honey: circadian clocks of bees and flowers and how their interactions may influence ecological communities”, “The Social Clock of the Honeybee” and Dmitri Nusinow (Danforth Plant Center) “Self-organizing, nuclear body formation by photoreceptors is required for photo-, thermo-, and circadian signaling.”
    *NOTE: date (2nd Friday) and location
  • February 2: Carsten Skarke (University of Pennsylvania) “The Human Chronobiome: A Paradigm for Circadian Medicine”, Erik Herzog (WashU Biology) “The promise of chronotherapy” 
  • March 2: Yo-El Ju (WashU Neurology), Matthew Tso (Herzog Lab, WashU Biology)
  • April 17* in BJCIH 7AB: Carl Johnson (Vanderbilt University) “Circadian Clocks and Luminescence Sensors: Applications to Neurobiological Questions”
    *NOTE: day and location
  • April 27*Anish Mitra (Raichle Lab, WashU Radiology), “Distinct trajectories in spontaneous infra-slow activity”; Qianyi Yang (Chen Lab, WashU Anesthesiology) “The Rhythm of Itch”
    *NOTE: date (4th Friday)
  • June 1: Chanung Wang (Holtzman Lab, WashU Neurology) “A Comparative Study of Sleep, Diurnal Patterns, and Eye Closure Between the House Mouse (Mus musculus) and African Spiny Mouse (Acomys cahirinus).”, Jeffrey Haspel (WashU Medicine) “The autophagy circadian proteome: effect of endotoxin and coordination with the proteasome”
  • July 6

All meetings are listed on the Neuroscience Calendar of the Office of Neuroscience Research.

Archives of previous seasons



Spring 2015

Clocks & Sleep Club Faculty

Faculty organizers: Erik Herzog, Paul Taghert, Michael Hughes

Affiliated Faculty

Erik Herzog (WashU Biology)
David Holtzman (WashU Neurology)
Michael Hughes (WashU Medicine)
Shin-Ichiro Imai (WashU Developmental Biology)
Yo-El Ju (WashU Neurology)
István Kiss (SLU Chemistry)
Brendan Lucey (WashU Neurology)
Erik Musiek (WashU Neurology)
Jeanne Nerbonne (WashU Medicine)
Dmitri Nusinow (Donald Danforth Plant Science Center)
Joshua Rubin (WashU Pediatrics)
Paul Shaw (WashU Dept. of Neuroscience)
Paul Taghert (WashU Dept. of Neuroscience)
Kelvin Yamada (WashU Neurology)

Archive of previous Clocks & Sleep Club meetings