Clocks & Sleep

Organizers: Erik Herzog, Paul Taghert, and Dmitri Nusinow Read More


The Hope Center is pleased to announce that Clocks & Sleep Club now is the Hope Center Clocks & Sleep Club.  This affiliation reflects an expansion of the existing group, aimed to help promote ongoing research on the role of sleep and circadian rhythms in neurodegenerative disease. The founders and organizers, Erik Herzog and Paul Taghert, will continue in their roles as the group meets monthly to discuss recent advances in the study of biological timing and sleep.

Labs working on biological rhythms include:

Erik Herzog. Molecules, cells and circuits of mammalian circadian timing.

Paul Taghert. Molecules, cells and circuits of insect circadian timing.

Dmitri Nusinow. Circadian regulation of physiology and development in plants.

David Holtzman. The role of normal and disrupted daily rhythms in amyloid beta production and Alzheimer’s Disease progression and therapies.

Michael Hughes. Daily regulation of gene expression.

Shin-Ichiro Imai. Epigenetics of circadian timing and aging.

Yo-El Ju. Sleep and neurological diseases.

Daniel Kerschensteiner. Neural circuits controlling circadian rhythms and sleep.

István Kiss. Coupled oscillator behavior in biological and electrochemical systems.

Brendan Lucey. Sleep and Alzheimer’s disease.

Erik Musiek. The role of clock genes and circadian rhythms in neurodegeneration.

Jeanne Nerbonne. Circadian regulation of excitability and channel biology.

Joshua Rubin. Chronotherapy for brain cancer.

Paul Shaw. Genetics and benefits of sleep.

Organizers/Contact Information

For additional information about the Clocks & Sleep Club, please contact

2020/2021 Schedule, Clocks & Sleep Club

1st Friday of the month
Zoom conference

For virtual meeting information email the Hope Center.

NOTE: Presenters have 30 minutes for slides and 15 minutes for questions.

  • June 5: Keenan Bates (Herzog lab, WashU Biology) “In Utero Imaging of Clock Gene Expression Reveals the Development of the Embryonic Circadian Clock”
  • July 10*: Chi Chan Lee (Kerschensteiner lab, WashU Ophthalmology & Visual Sciences) “Investigate the role of intergeniculate leaflet in circadian rhythm”
    NOTE *2nd Friday
  • August 7: Paul Taghert (WashU Dept. of Neuroscience) “On the timing of GPCR signaling in circadian physiology”, Nithya Chennupati (Ju lab, WashU Neurology) “Race effects on sleep, circadian function, and Alzheimer Disease biomarkers”
  • September 4: Samira Parhizkar (Holtzman lab, WashU Neurology) “Sleep Disruption Exacerbates and Prolongs the Inflammatory Response to Traumatic Brain Injury”, Jeffrey Haspel (WashU Medicine) “What’s out there about circadian rhythms and COVID-19?”
  • September 11*: Erik Herzog (WashU Biology), Michael Hughes (WashU Medicine), Peinan Zhao (WashU Obstetrics/Gynecology) “A Workshop: Time series analysis and measures from wearable devices”
    *Special workshop
  • October 9*: Melvin King (Musiek lab, WashU Neurology) “Central vs. peripheral clocks in neurodegeneration”, Lara Pferdehirt (Guilak lab, WashU Orthopaedic Surgery) “Turning back the clock on cartilage damage”
    NOTE *2nd Friday
  • November 6: Maria Sorkin (Nusinow lab, Danforth Plant Science Center) “A Proteomic Approach Discovers a Putative Cold Temperature Regulatory Complex in the Arabidopsis Circadian Clock​”, Eric Landsness (WashU Neurology) “Deep Learning of Non-Invasive Calcium Imaging Reliably Classifies Sleep States in Mice”
  • December 4: Geraldine Kress (WashU Neurology) “A journal club discussion on two recent articles about the circadian system and sleep”
    Suggested Readings:
    “Circadian VIPergic Neurons of the Suprachiasmatic Nuclei Sculpt the Sleep-Wake Cycle”  
    Neuron 2020
    “Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations”  Nature Communications 2020
     Ronald McCarthy (England lab, WashU Obstetrics & Gynecology) “Association between daily melatonin and cortisol rhythms and risk of preterm birth”
  • January 8*: Chao Zhou (WashU Biomedical Engineering)
    NOTE *2nd Friday

All meetings are listed on the Office of Neuroscience Research (ONR) Calendar.

Archives of previous seasons






Spring 2015

Clocks & Sleep Club Faculty

Faculty organizers: Erik Herzog, Paul Taghert, Dmitri Nusinow

Affiliated Faculty

Ryan Bogdan (WashU Psychological & Brain Sciences)
Thomas Burris (St. Louis College of Pharmacy/WashU Anesthesiology)
Yao Chen (WashU Dept. of Neuroscience)
Meaghan Creed (WashU Anesthesiology)
Jeffrey Haspel (WashU Medicine)
Erik Herzog (WashU Biology)
David Holtzman (WashU Neurology)
Michael Hughes (WashU Medicine)
Shin-Ichiro Imai (WashU Developmental Biology)
Yo-El Ju (WashU Neurology)
Daniel Kerschensteiner (WashU Ophthalmology & Visual Sciences)
Jonathan Kipnis (WashU Pathology & Immunology)
István Kiss (SLU Chemistry)
Geraldine Kress (WashU Neurology)
Brendan Lucey (WashU Neurology)
Tim Miller (WashU Neurology)
Erik Musiek (WashU Neurology)
Jeanne Nerbonne (WashU Medicine)
Aaron Norris (WashU Anesthesiology)
Dmitri Nusinow (Donald Danforth Plant Science Center)
Thomas Papouin (WashU Dept. of Neuroscience)
Laura Piccio (WashU Neurology)
Joshua Rubin (WashU Pediatrics)
Paul Shaw (WashU Dept. of Neuroscience)
Paul Taghert (WashU Dept. of Neuroscience)
Kelvin Yamada (WashU Neurology)
Andrew Yoo (WashU Developmental Biology)
Guoyan Zhao (WashU Dept. of Neuroscience)
Chao Zhou (WashU Biomedical Engineering)

Archive of previous Clocks & Sleep Club meetings