Stefanie Geisler, MD

Assistant Professor of Neurology

Mechanisms of axonal degeneration in peripheral neuropathies Read More

Email: geislers@wustl.edu
Lab Phone: (314) 273-3087
Website: Geisler Lab
Lab Location: Biotech Building 104, 105
Keywords: axonal degeneration, axonal regeneration, peripheral neuropathies, genetics

Mechanisms of axonal degeneration in peripheral neuropathies

Peripheral neuropathies are the most prevalent neurodegenerative diseases, affecting more than 20 million patients in the US alone.  Many peripheral neuropathies are characterized by early axonal degeneration.  Yet the mechanisms leading to axonal degeneration remain poorly understood and no therapies exist to directly target the destructive process. In our laboratory, we integrate information from cell and animal models with genetic data from patients to gain insight into molecular mechanisms underlying axon degeneration and regeneration. The goal of our laboratory is to identify new therapeutic agents that can be translated into relevant treatment strategies for patients suffering from peripheral neuropathies and possibly other neurodegenerative diseases.

Hope Center Affiliations

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