Neurodegeneration/HPAN

Beau Ances, MD, PhD
Daniel J. Brennan, MD Professor, WashU Neurology
- Phone: 314-747-8423
- Email: bances@wustl.edu
Therapeutic Strategies for HIV Associated Neurocognitive Impairment

Ghazal Ashrafi, PhD
Assistant Professor, WashU Cell Biology & Physiology
- Phone: 314-273-1870
- Email: ghazaleh@wustl.edu
Metabolic regulation of neurotransmission

Yuna Ayala, PhD
Associate Professor and Vice Chair, SLU Biochemistry & Molecular Biology
- Phone: 314-977-9247
- Email: yayala@slu.edu
Role of RNA processing and TDP-43 function in neurodegeneration

Randall Bateman, MD
Charles F. and Joanne Knight Distinguished Professor, WashU Neurology
- Phone: 314-747-7066
- Email: batemanr@wustl.edu
Alzheimer’s Disease: Pathophysiology, biomarkers, predictive diagnostics, treatments

Tammie Benzinger, MD, PhD
Professor, WashU Radiology
- Phone: 314-362-1558
- Email: benzingert@wustl.edu
b-amyloid (Ab) pathology and Alzheimer Disease (AD)

Kendall Blumer, PhD
Professor, WashU Cell Biology & Physiology
- Phone: 314-362-1662
- Email: kblumer@wustl.edu
Signal transduction in the cardiovascular, nervous and visual systems

Thomas Brett, PhD
Associate Professor, WashU Medicine
- Phone: 314-747-0049
- Email: tbrett@wustl.edu
Molecular mechanisms of inflammatory signaling in diseases hallmarked by chronic inflammation

Anil Cashikar, PhD
Associate Professor, WashU Psychiatry
- Phone: 314-273-1863
- Email: cashikar@wustl.edu
Oxysterols in Alzheimer’s disease

Aisling Chaney, PhD
Assistant Professor, WashU Radiology
- Phone: 314-362-8461
- Email: achaney@wustl.edu
Molecular Imaging of Neuroimmune responses in Degeneration (MIND)

John Cirrito, PhD
Associate Professor, WashU Neurology
- Phone: 314-362-1664
- Email: cirritoj@wustl.edu
Relationship between synaptic activity and amyloid-beta metabolism in Alzheimer’s disease

Marco Colonna, MD
Robert Rock Belliveau MD Professor, WashU Pathology & Immunology
- Phone: 314-362-0368
- Email: mcolonna@wustl.edu
Innate immune responses in neurodegeneration

Carlos Cruchaga, PhD
Barbara Burton and Reuben M. Morriss III Professor, WashU Psychiatry
- Phone: 314-286-0546
- Email: cruchagac@wustl.edu
Genetic and multi-omic approaches to identify novel variants, genes and pathways

Albert (Gus) Davis, MD, PhD
Assistant Professor, WashU Neurology
- Phone: 314-273-7763
- Email: albert.a.davis@wustl.edu
Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies

Abhinav Diwan, MD
Professor, WashU Medicine
- Phone: 314-362-1984
- Email: adiwan@wustl.edu
Regulation of Lysosome function in Cellular Physiology and Pathology

Gabor Egervari, MD, PhD
Assistant Professor, WashU Genetics and Biochemistry and Molecular Biophysics
- Email: gabor@wustl.edu
Metabolic-epigenetic interactions in the healthy and diseased brain

Susan Farr, PhD
Professor, SLU Internal Medicine
- Phone: 314-977-6084
- Email: susan.farr@health.slu.edu
Age-related neurodegeneration leading to dementia

Liberty Francois-Moutal, PhD
Research Assistant Professor, SLU Pharmacology and Physiology
Synaptic delivery of mRNA in neurodegeneration and painful neuropathies

Carl Frieden, PhD
Professor, WashU Biochemistry & Molecular Biophysics
- Phone: 314-362-3342
- Email: friedenc@wustl.edu
Protein folding, structure

Gilbert Gallardo, PhD
Assistant Professor, WashU Neurology
- Phone: 314-362-7813
- Email: g.gallardo@wustl.edu
Discovering mechanisms of neurodegeneration for potential therapeutic intervention

Brian Gordon, PhD
Assistant Professor, WashU Radiology
- Phone: 314-747-7354
- Email: bagordon@wustl.edu
Using in vivo neuroimaging and biofluid measurements in humans to better understand the pathophysiology of Alzheimer disease

Dennis Hallahan, MD
Elizabeth H. and James S. McDonnell, III Distinguished Professor of Medicine and Head, WashU Radiation Oncology
- Phone: 314-362-9700
- Email: dhallahan@wustl.edu
The mechanisms of cell death in normal tissues during cancer therapy

Edward Han, PhD
Assistant Professor, WashU Neuroscience
- Phone: 314-747-2505
- Email: ehan23@wustl.edu
Identifying the role of neurotoxic protein aggregates on neuronal network activity and cell health using in vivo imaging

Tamara Hershey, PhD
James S. McDonnell Professor of Cognitive Neuroscience, WashU Psychiatry
- Phone: 314-362-5593
- Email: tammy@wustl.edu
Clinical and cognitive neuroscience

Keiko Hirose, MD
Professor, WashU Otolaryngology
- Phone: 314-454-4033
- Email: hirosek@wustl.edu
Innate immunity in the inner ear

David Holtzman, MD
Hope Center Scientific Director; Barbara Burton and Reuben M. Morriss III Distinguished Professor, WashU Neurology
- Phone: 314-747-0286
- Email: holtzman@wustl.edu
Cellular/Molecular/ Biomarker studies of Alzheimer’s Disease and neonatal brain injury

Song Hu, PhD
Associate Professor, WashU Biomedical Engineering
- Phone: 314-935-3637
- Email: songhu@wustl.edu
Optical and photoacoustic imaging

Meredith Jackrel, PhD
Assistant Professor, WashU Chemistry
- Phone: 314-935-6530
- Email: mjackrel@wustl.edu
Engineering and applying protein-remodeling factors to counter neurodegenerative disease

Sanjay Jain, PhD
Professor, WashU Medicine
- Phone: 314-454-8728
- Email: sanjayjain@wustl.edu
GFL-Ret mediated mechanisms in the development, repair and regeneration of the nervous and urogenital systems

Celeste Karch, PhD
Professor, WashU Psychiatry
- Phone: 314-747-3161
- Email: karchc@wustl.edu
Molecular mechanisms underlying tauopathies

Jonathan Kipnis, PhD
BJC Investigator, Alan A. and Edith L. Wolff Distinguished Professor, WashU Pathology & Immunology
- Phone: 314-273-2288
- Email: kipnis@wustl.edu
Complex interactions between the immune system and the central nervous system (CNS) in health and disease

Paul Kotzbauer, MD, PhD
Professor, WashU Neurology
- Email: kotzbauerp@wustl.edu
Mechanisms of neurodegeneration in Parkinson’s disease and related disorders

Alexxai Kravitz, PhD
Associate Professor, WashU Psychiatry
- Phone: 314-362-5184
- Email: alexxai@wustl.edu
Basal ganglia contributions to movement

Geraldine Kress, PhD
Assistant Professor, WashU Neurology
- Phone: 314-362-5503
- Email: kress.g.j@wustl.edu
Role of circadian function on memory during aging and Alzheimer’s disease (AD) progression

Terrance Kummer, MD, PhD
Associate Professor, WashU Neurology
- Phone: 314-362-2999
- Email: kummert@wustl.edu
Mechanisms of neuronal injury in acute brain trauma and its link to neurodegeneration

Jin-Moo Lee, MD, PhD
Andrew B. & Gretchen P. Jones Professor and Chair, WashU Neurology
- Phone: 314-362-7382
- Email: leejm@wustl.edu
Understanding mechanisms of neurologic disease

Mingjie Li, MD, PhD
Associate Professor, WashU Neurology
- Phone: 314-747-1123
- Email: lim@wustl.edu
Developing viral vectors for applications in neuroscience

Tristan Qingyun Li, PhD
Assistant Professor, WashU Neuroscience
- Phone: 314-273-1422
- Email: qingyunli@wustl.edu
Research Interests:
Microglial biology and neuro-immune interaction underlying brain structure and disease

Brendan Lucey, MD
Professor, WashU Neurology
- Phone: 314-747-3805
- Email: luceyb@wustl.edu
Understanding the relationship between sleep, the amyloid beta diurnal pattern, and Alzheimer’s disease

Moe Mahjoub, PhD
Associate Professor, WashU Medicine
- Phone: 314-362-5681
- Email: mmahjoub@wustl.edu
Mechanisms of cell-cell signaling in normal development and neurodegenerative disease

Soe Soe Mar, MD
Professor, WashU Neurology
- Phone: 314-454-6226
- Email: mars@wustl.edu
Pediatric multiple sclerosis and other white matter diseases, and pediatric migraine

Helen McNeill, PhD
BJC Investigator, Larry J. Shapiro and Carol-Ann Uetake-Shapiro Professor, WashU Developmental Biology
- Phone: 314-273-3050
- Email: mcneillh@wustl.edu
Understanding how Fat cadherins and the Hippo pathway regulate growth and patterning

Steven Mennerick, PhD
John P. Feighner Professor of Neuropsychopharmacology, WashU Psychiatry
- Phone: 314-747-2988
- Email: menneris@wustl.edu
Physiology of glutamate and GABA neurotransmission in the CNS

Timothy Miller, MD, PhD
David Clayson Professor, WashU Neurology
- Phone: 314-362-8169
- Email: miller.t@wustl.edu
New, effective, and safe treatments for neurodegenerative diseases

John Morris, MD
Harvey A & Dorismae Hacker Friedman Distinguished Professor, WashU Neurology
- Phone: 314-286-2881
- Email: jcmorris@wustl.edu
Establishing phenotypes for inherited forms of Alzheimer’s disease and other dementias

Erik Musiek, MD, PhD
Charlotte & Paul Hagemann Professor, WashU Neurology
- Phone: 314-747-5412
- Email: musieke@wustl.edu
Aging, oxidative stress, and circadian clock genes in neurodegenerative diseases

Andrew Nguyen, PhD
Assistant Professor, SLU Medicine
- Phone: 314-977-5308
- Email: andy.d.nguyen@health.slu.edu
Strategies for increasing progranulin levels as potential therapies for progranulin-deficient FTD

David Ornitz, MD, PhD
Alumni Endowed Professor, WashU Developmental Biology
- Phone: 314-362-5074
- Email: dornitz@wustl.edu
Neuronal development, regeneration, physiology

Rohit Pappu, PhD
Gene K. Beare Distinguished Professor, WashU Biomedical Engineering
- Phone: 314-935-5416
- Email: pappu@wustl.edu
Mechanisms of aggregation and neurodegeneration in polyglutamine expansion disorders, specifically Huntington’s disease

Steven Paul, MD
Professor, WashU Psychiatry
- Phone: 314-273-1863
- Email: smpaul@wustl.edu
Understanding how apoE contributes to the clearance and metabolism of Aβ in Alzheimer’s disease

David Perlmutter, MD
Professor of Pediatrics, Executive Vice Chancellor for Medical Affairs and Dean, WashU School of Medicine
- Phone: 314-286-2249
- Email: perlmutterd@wustl.edu
Cellular mechanisms to clear misfolded proteins, and therapies to minimize toxicity by stimulating degradation of misfolded proteins