Neurodegeneration/HPAN
![John Morris, MD](https://hopecenter.wustl.edu/files/2020/03/MorrisJohn_web-280x386.jpg)
John Morris, MD
Harvey A & Dorismae Hacker Friedman Distinguished Professor, WashU Neurology
- Phone: 314-286-2881
- Email: jcmorris@wustl.edu
Establishing phenotypes for inherited forms of Alzheimer’s disease and other dementias
![Erik Musiek, MD, PhD](https://hopecenter.wustl.edu/files/2020/03/MusiekErik_web.jpg)
Erik Musiek, MD, PhD
Charlotte & Paul Hagemann Professor, WashU Neurology
- Phone: 314-747-5412
- Email: musieke@wustl.edu
Aging, oxidative stress, and circadian clock genes in neurodegenerative diseases
![Arash Nazeri, MD](https://hopecenter.wustl.edu/files/2024/03/NazeriArash_web-f0384f51a97ca50b-280x386.jpg)
Arash Nazeri, MD
Assistant Professor, WashU Radiology
- Email: a.nazeri@wustl.edu
Neuroimaging biomarkers of brain fluid compartments and tools for enhanced drug delivery
![Andrew Nguyen, PhD](https://hopecenter.wustl.edu/files/2020/03/NguyenAndrew_web-280x386.jpg)
Andrew Nguyen, PhD
Assistant Professor, SLU Medicine
- Phone: 314-977-5308
- Email: andy.d.nguyen@health.slu.edu
Strategies for increasing progranulin levels as potential therapies for progranulin-deficient FTD
![Susan Nielsen, PhD](https://hopecenter.wustl.edu/files/2024/12/NielsenSusan_Neurology.png)
Susan Nielsen, PhD
Associate Professor, WashU Neurology
- Phone: 314-747-2211
- Email: snielsen@wustl.edu
Understanding etiology and identifying approaches for prevention and treatment of Parkinson disease and ALS
![Kevin Noguchi, PhD](https://hopecenter.wustl.edu/files/2024/12/NoguchiKevin_Psychiatry-web-280x386.jpg)
Kevin Noguchi, PhD
Associate Professor, WashU Psychiatry
- Phone: 314-362-7007
- Email: noguchik@wustl.edu
Neuropathology in the developing brain
![David Ornitz, MD, PhD](https://hopecenter.wustl.edu/files/2020/03/OrnitzDavid_web-280x386.jpg)
David Ornitz, MD, PhD
Alumni Endowed Professor, WashU Developmental Biology
- Phone: 314-362-5074
- Email: dornitz@wustl.edu
Neuronal development, regeneration, physiology
![Rohit Pappu, PhD](https://hopecenter.wustl.edu/files/2020/03/PappuRohit_web-280x386.png)
Rohit Pappu, PhD
Gene K. Beare Distinguished Professor, WashU Biomedical Engineering
- Phone: 314-935-5416
- Email: pappu@wustl.edu
Mechanisms of aggregation and neurodegeneration in polyglutamine expansion disorders, specifically Huntington’s disease
![Steven Paul, MD](https://hopecenter.wustl.edu/files/2020/03/PaulSteven_web-280x386.jpg)
Steven Paul, MD
Professor, WashU Psychiatry
- Phone: 314-273-1863
- Email: smpaul@wustl.edu
Understanding how apoE contributes to the clearance and metabolism of Aβ in Alzheimer’s disease
![David Perlmutter, MD](https://hopecenter.wustl.edu/files/2020/03/PerlmutterDavid_2023-280x386.jpg)
David Perlmutter, MD
Professor of Pediatrics, Executive Vice Chancellor for Medical Affairs and Dean, WashU School of Medicine
- Phone: 314-286-2249
- Email: perlmutterd@wustl.edu
Cellular mechanisms to clear misfolded proteins, and therapies to minimize toxicity by stimulating degradation of misfolded proteins
![Joel Perlmutter, MD](https://hopecenter.wustl.edu/files/2020/03/PerlmutterJoel_2022-280x386.jpg)
Joel Perlmutter, MD
Elliot Stein Professor, WashU Neurology
- Phone: 314-362-6909
- Email: perlmutterjoel@wustl.edu
Pharmacology, physiology and pathophysiology of basal ganglia and movement disorders
![Richard Perrin, MD, PhD](https://hopecenter.wustl.edu/files/2020/03/PerrinRichard_web-280x386.jpg)
Richard Perrin, MD, PhD
Associate Professor, WashU Pathology & Immunology
- Phone: 314-747-5713
- Email: rperrin@wustl.edu
Novel cerebrospinal fluid biomarkers for early diagnosis, prognosis, and staging of neurodegenerative diseases
![Alan Pestronk, MD](https://hopecenter.wustl.edu/files/2020/03/PestronkAlan_neurology-280x386.jpg)
Alan Pestronk, MD
Professor, WashU Neurology
- Phone: 314-362-6981
- Email: pestronka@wustl.edu
Diagnosis, pathogenesis and treatment of immune, hereditary and degenerative neuromuscular disorders
![Steve Petersen, PhD](https://hopecenter.wustl.edu/files/2020/03/PetersenSteven_2022-280x386.jpg)
Steve Petersen, PhD
Professor Emeritus, WashU Neurology
- Phone: 314-362-3317
- Email: sep@wustl.edu
Behavioral and fMRI studies of attention and cognitive development
![Nicola Pozzi, PhD](https://hopecenter.wustl.edu/files/2020/03/PozziNicola_web.jpg)
Nicola Pozzi, PhD
Assistant Professor, SLU Biochemistry and Molecular Biology
- Phone: 314-977-9257
- Email: npozzi@slu.edu
Molecular mechanisms of thrombosis and immunothrombosis
![Marcus Raichle, MD](https://hopecenter.wustl.edu/files/2020/03/RaichleMarcus_2022-280x386.jpg)
Marcus Raichle, MD
Alan A. and Edith L. Wolff Distinguished Professor of Medicine, WashU Radiology
- Phone: 314-362-6907
- Email: mraichle@wustl.edu
Functional brain imaging with positron emission tomography and magnetic resonance
![Naresha Saligrama, PhD](https://hopecenter.wustl.edu/files/2020/03/SaligramaNaresha_web-1-280x386.jpg)
Naresha Saligrama, PhD
Assistant Professor, WashU Neurology
- Phone: 314-273-8540
- Email: nareshas@wustl.edu
Neuroimmune interactions in health and neurological disorders
![Daniela Salvemini, PhD](https://hopecenter.wustl.edu/files/2020/03/SalveminiDaniela_web.jpg)
Daniela Salvemini, PhD
William Beaumont Professor and Chair, SLU Pharmacology and Physiology
- Phone: 314-977-6430
- Email: daniela.salvemini@health.slu.edu
A translational bench to bedside approach towards the discovery of novel analgesics
![Mark Sands, PhD](https://hopecenter.wustl.edu/files/2020/03/SandsMark_medicine-280x386.jpg)
Mark Sands, PhD
Professor, WashU Medicine
- Phone: 314-362-5496
- Email: msands@wustl.edu
Pathophysiology and novel therapies for lysosomal storage diseases
![Anneliese Schaefer, JD, PhD](https://hopecenter.wustl.edu/files/2019/11/SchaeferAnneliese_web-280x386.jpg)
Anneliese Schaefer, JD, PhD
Hope Center Executive Director; Professor, WashU Neurology
- Phone: 314-747-3429
- Email: amschaefer@wustl.edu
Motor neuron disease
![Suzanne Schindler, MD, PhD](https://hopecenter.wustl.edu/files/2024/02/SchindlerSuzanne_web-7369149d8df2d2f5-280x386.jpg)
Suzanne Schindler, MD, PhD
Associate Professor, WashU Neurology
- Phone: 314-273-1655
- Email: schindler.s.e@wustl.edu
Fluid biomarkers of Alzheimer disease
![Ikbal Sencan-Egilmez, PhD](https://hopecenter.wustl.edu/files/2022/12/Sencan-EgilmezIkbal_web-280x386.jpg)
Ikbal Sencan-Egilmez, PhD
Assistant Professor, WashU Radiology
- Phone: 314-273-5458
- Email: ikbal@wustl.edu
Development and use of advanced optical microscopy solutions for preclinical imaging studies in brain and beyond
![Lori Setton, PhD](https://hopecenter.wustl.edu/files/2021/06/SettonLori.jpg)
Lori Setton, PhD
Lucy & Stanley Lopata Distinguished Professor and Chair, WashU Biomedical Engineering
- Phone: 314-935-8612
- Email: setton@wustl.edu
Combines methods of engineering & biology to regulate disc and cartilage health and healing
![B. Joy Snider, MD, PhD](https://hopecenter.wustl.edu/files/2020/03/SniderB.Joy_-280x386.jpg)
B. Joy Snider, MD, PhD
Professor, WashU Neurology
- Phone: 314-362-4872
- Email: sniderj@wustl.edu
Alzheimer disease and other dementias, including diagnosis, treatment, clinical trials and biomarkers and medical education in dementia
![Amber Stratman, PhD](https://hopecenter.wustl.edu/files/2020/03/stratmanamber-cellbio-280x386.jpg)
Amber Stratman, PhD
Assistant Professor, WashU Cell Biology & Physiology
- Phone: 314-273-7927
- Email: a.stratman@wustl.edu
Mechanisms regulating blood vessel formation, stabilization, and blood flow sensing during development and disease
![Heather True, PhD](https://hopecenter.wustl.edu/files/2020/03/TrueHeather-280x386.jpg)
Heather True, PhD
Professor, WashU Cell Biology & Physiology
- Phone: 314-362-3927
- Email: heather.true@wustl.edu
Protein misfolding and aggregation of prion proteins
![Fumihiko Urano, MD, PhD](https://hopecenter.wustl.edu/files/2020/01/UranoFumihiko_forweb-280x386.jpg)
Fumihiko Urano, MD, PhD
Samuel E. Schechter Professor, WashU Medicine
- Phone: 314-362-8683
- Email: urano@wustl.edu
Therapies for Wolfram syndrome; role of endoplasmic reticulum in neurodegeneration
![Andrei Vlassenko, MD, PhD](https://hopecenter.wustl.edu/files/2020/03/VlassenkoAndrei_2022-280x386.jpg)
Andrei Vlassenko, MD, PhD
Associate Professor, WashU Radiology
- Phone: 314-362-3301
- Email: andreigvlassenko@wustl.edu
Advanced neuroimaging techniques in aging and neurodegenerative disorders
![Yong Wang, PhD](https://hopecenter.wustl.edu/files/2020/03/WangYong_web.jpg)
Yong Wang, PhD
Associate Professor, WashU Obstetrics & Gynecology
- Phone: 314-286-2408
- Email: wangyong@wustl.edu
Research Interests:
Developing and applying MRI methods for quantification of pathological changes in neurodegeneration diseases
![Conrad (Chris) Weihl, MD, PhD](https://hopecenter.wustl.edu/files/2019/12/WeihlConrad_forweb.jpg)
Conrad (Chris) Weihl, MD, PhD
Professor, WashU Neurology
- Phone: 314-747-6394
- Email: weihlc@wustl.edu
Protein degradation pathways in relation to aging, muscle weakness and neurodegeneration
![Hiroko Yano, PhD](https://hopecenter.wustl.edu/files/2020/01/YanoHiroko-2023-280x386.jpg)
Hiroko Yano, PhD
Associate Professor, WashU Neurosurgery
- Phone: 314-747-6012
- Email: yanoh@wustl.edu
Molecular pathogenesis of neurodegeneration; Epigenetic regulation in Huntington’s disease
![Andrew Yoo, PhD](https://hopecenter.wustl.edu/files/2020/03/YooAndrew_web-1-280x386.jpg)
Andrew Yoo, PhD
Professor, WashU Developmental Biology
- Phone: 314-362-1814
- Email: yooa@wustl.edu
MicroRNA-mediated neuronal reprogramming and chromatin remodeling
![Gregory Zipfel, MD](https://hopecenter.wustl.edu/files/2020/01/ZipfelGregory-2023-280x386.jpg)
Gregory Zipfel, MD
Ralph G. Dacey Distinguished Professor and Chair, WashU Neurosurgery
- Phone: 314-747-8871
- Email: zipfelg@wustl.edu
Cerebral amyloid angiopathy; Aneurysmal subarachnoid hemorrhage