Neurodegeneration/HPAN
![Beau Ances, MD, PhD](https://hopecenter.wustl.edu/files/2020/01/AncesBeau_2022-280x386.jpg)
Beau Ances, MD, PhD
Daniel J. Brennan, MD Professor, WashU Neurology
- Phone: 314-747-8423
- Email: bances@wustl.edu
Therapeutic Strategies for HIV Associated Neurocognitive Impairment
![Ghazal Ashrafi, PhD](https://hopecenter.wustl.edu/files/2021/06/AshrafiGhazaleh-2023-280x386.jpg)
Ghazal Ashrafi, PhD
Assistant Professor, WashU Cell Biology & Physiology
- Phone: 314-273-1870
- Email: ghazaleh@wustl.edu
Metabolic regulation of neurotransmission
![John Atkinson, MD](https://hopecenter.wustl.edu/files/2020/01/atkinsonJohn_medicine-280x386.jpg)
John Atkinson, MD
Samuel B. Grant Professor, WashU Medicine
- Phone: 314-362-8391
- Email: j.p.atkinson@wustl.edu
Etiopathogenesis, clinical course, and treatment/cure of TREX-1 vasculopathy
![Yuna Ayala, PhD](https://hopecenter.wustl.edu/files/2020/01/AyalaYuna-SLU-280x386.png)
Yuna Ayala, PhD
Associate Professor and Vice Chair, SLU Biochemistry & Molecular Biology
- Phone: 314-977-9247
- Email: yayala@slu.edu
Role of RNA processing and TDP-43 function in neurodegeneration
![Randall Bateman, MD](https://hopecenter.wustl.edu/files/2020/01/BatemanRandall_2024-280x386.jpg)
Randall Bateman, MD
Charles F. and Joanne Knight Distinguished Professor, WashU Neurology
- Phone: 314-747-7066
- Email: batemanr@wustl.edu
Alzheimer’s Disease: Pathophysiology, biomarkers, predictive diagnostics, treatments
![Tammie Benzinger, MD, PhD](https://hopecenter.wustl.edu/files/2021/02/BenzingerTammie_2022-280x386.jpg)
Tammie Benzinger, MD, PhD
Hugh Monroe Wilson Professor, WashU Radiology
- Phone: 314-362-1558
- Email: benzingert@wustl.edu
b-amyloid (Ab) pathology and Alzheimer Disease (AD)
![Kendall Blumer, PhD](https://hopecenter.wustl.edu/files/2020/01/BlumerKendall_forweb-280x386.jpg)
Kendall Blumer, PhD
Professor, WashU Cell Biology & Physiology
- Phone: 314-362-1662
- Email: kblumer@wustl.edu
Signal transduction in the cardiovascular, nervous and visual systems
![Thomas Brett, PhD](https://hopecenter.wustl.edu/files/2020/01/BrettTom-280x386.jpg)
Thomas Brett, PhD
Associate Professor, WashU Medicine
- Phone: 314-747-0049
- Email: tbrett@wustl.edu
Molecular mechanisms of inflammatory signaling in diseases hallmarked by chronic inflammation
![Anil Cashikar, PhD](https://hopecenter.wustl.edu/files/2020/01/CashikarAnil_web.jpg)
Anil Cashikar, PhD
Associate Professor, WashU Psychiatry
- Phone: 314-273-1863
- Email: cashikar@wustl.edu
Oxysterols in Alzheimer’s disease
![Aisling Chaney, PhD](https://hopecenter.wustl.edu/files/2023/02/ChaneyAisling-web-280x386.jpg)
Aisling Chaney, PhD
Assistant Professor, WashU Radiology
- Phone: 314-362-8461
- Email: achaney@wustl.edu
Molecular Imaging of Neuroimmune responses in Degeneration (MIND)
![Jaehyung (Gus) Cho, PhD](https://hopecenter.wustl.edu/files/2021/06/ChoGus-280x386.png)
Jaehyung (Gus) Cho, PhD
Professor, WashU Medicine
- Phone: 314-362-8804
- Email: jaehyung.cho@wustl.edu
Mechanisms of platelet and neutrophil activation in thrombosis and inflammation
![John Cirrito, PhD](https://hopecenter.wustl.edu/files/2020/02/CirritoJohn_web-280x386.jpg)
John Cirrito, PhD
Professor, WashU Neurology
- Phone: 314-362-1664
- Email: cirritoj@wustl.edu
Relationship between synaptic activity and amyloid-beta metabolism in Alzheimer’s disease
![Marco Colonna, MD](https://hopecenter.wustl.edu/files/2020/02/ColonnaMarco_web-2022-280x386.jpg)
Marco Colonna, MD
Robert Rock Belliveau MD Professor, WashU Pathology & Immunology
- Phone: 314-362-0368
- Email: mcolonna@wustl.edu
Innate immune responses in neurodegeneration
![Carlos Cruchaga, PhD](https://hopecenter.wustl.edu/files/2019/12/CruchagaCarlos_2022-web-280x386.jpg)
Carlos Cruchaga, PhD
Barbara Burton and Reuben M. Morriss III Professor, WashU Psychiatry
- Phone: 314-286-0546
- Email: cruchagac@wustl.edu
Genetic and multi-omic approaches to identify novel variants, genes and pathways
![Ralph Dacey, MD](https://hopecenter.wustl.edu/files/2020/01/DaceyRalph_web-280x386.jpg)
Ralph Dacey, MD
Henry G & Edith Schwartz Professor, WashU Neurosurgery
- Phone: 314-362-3571
- Email: daceyr@wustl.edu
Regulatory mechanisms of the cerebrovascular microcirculation
![Albert (Gus) Davis, MD, PhD](https://hopecenter.wustl.edu/files/2020/02/DavisGus_web-280x386.jpg)
Albert (Gus) Davis, MD, PhD
Assistant Professor, WashU Neurology
- Phone: 314-273-7763
- Email: albert.a.davis@wustl.edu
Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies
![Abhinav Diwan, MD](https://hopecenter.wustl.edu/files/2020/02/DiwanAbhinav_web-280x386.jpg)
Abhinav Diwan, MD
Charlie W. Shaeffer, M.D. Professor, WashU Medicine
- Phone: 314-362-1984
- Email: adiwan@wustl.edu
Regulation of Lysosome function in Cellular Physiology and Pathology
![Nico Dosenbach, MD, PhD](https://hopecenter.wustl.edu/files/2020/01/DosenbachNico_web-280x386.jpg)
Nico Dosenbach, MD, PhD
Associate Professor, WashU Neurology
- Phone: 314-454-6006
- Email: dosenbachn@wustl.edu
Use-driven brain network plasticity in children with brain injury
![Gabor Egervari, MD, PhD](https://hopecenter.wustl.edu/files/2023/03/Egervari-Gabor-280x386.jpg)
Gabor Egervari, MD, PhD
Assistant Professor, WashU Genetics and WashU Biochemistry and Molecular Biophysics
- Email: gabor@wustl.edu
Metabolic-epigenetic interactions in the healthy and diseased brain
![Susan Farr, PhD](https://hopecenter.wustl.edu/files/2022/11/FarrSusan_SLU-280x386.jpg)
Susan Farr, PhD
Professor, SLU Internal Medicine
- Phone: 314-977-6084
- Email: susan.farr@health.slu.edu
Age-related neurodegeneration leading to dementia
![Liberty Francois-Moutal, PhD](https://hopecenter.wustl.edu/files/2022/10/Francois-MoutalLiberty-SLU-280x386.jpg)
Liberty Francois-Moutal, PhD
Research Assistant Professor, SLU Pharmacology and Physiology
Synaptic delivery of mRNA in neurodegeneration and painful neuropathies
![Carl Frieden, PhD](https://hopecenter.wustl.edu/files/2020/02/friedencarl_bcmp-280x386.jpg)
Carl Frieden, PhD
Professor, WashU Biochemistry & Molecular Biophysics
- Phone: 314-362-3342
- Email: friedenc@wustl.edu
Protein folding, structure
![Gilbert Gallardo, PhD](https://hopecenter.wustl.edu/files/2020/02/GallardoGilbert-hcweb-280x386.jpg)
Gilbert Gallardo, PhD
Assistant Professor, WashU Neurology
- Phone: 314-362-7813
- Email: g.gallardo@wustl.edu
Discovering mechanisms of neurodegeneration for potential therapeutic intervention
![Brian Gordon, PhD](https://hopecenter.wustl.edu/files/2020/02/GordonBrian_2022-280x386.jpg)
Brian Gordon, PhD
Assistant Professor, WashU Radiology
- Phone: 314-747-7354
- Email: bagordon@wustl.edu
Using in vivo neuroimaging and biofluid measurements in humans to better understand the pathophysiology of Alzheimer disease
![Dennis Hallahan, MD](https://hopecenter.wustl.edu/files/2020/02/HallahanDennis_web.jpg)
Dennis Hallahan, MD
Elizabeth H. and James S. McDonnell, III Distinguished Professor of Medicine and Head, WashU Radiation Oncology
- Phone: 314-362-9700
- Email: dhallahan@wustl.edu
The mechanisms of cell death in normal tissues during cancer therapy
![Edward Han, PhD](https://hopecenter.wustl.edu/files/2020/02/Han-Edward-2022-280x386.jpg)
Edward Han, PhD
Assistant Professor, WashU Neuroscience
- Phone: 314-747-2505
- Email: ehan23@wustl.edu
Identifying the role of neurotoxic protein aggregates on neuronal network activity and cell health using in vivo imaging
![Tamara Hershey, PhD](https://hopecenter.wustl.edu/files/2020/02/HersheyTamara_2022-280x386.jpg)
Tamara Hershey, PhD
James S. McDonnell Professor of Cognitive Neuroscience, WashU Psychiatry
- Phone: 314-362-5593
- Email: tammy@wustl.edu
Clinical and cognitive neuroscience
![Keiko Hirose, MD](https://hopecenter.wustl.edu/files/2022/12/Keiko-Hirose-oto-280x386.jpg)
Keiko Hirose, MD
Professor, WashU Otolaryngology
- Phone: 314-454-4033
- Email: hirosek@wustl.edu
Innate immunity in the inner ear
![David Holtzman, MD](https://hopecenter.wustl.edu/files/2019/11/HoltzmanDavid-2022-280x386.jpg)
David Holtzman, MD
Hope Center Scientific Director; Barbara Burton and Reuben M. Morriss III Distinguished Professor, WashU Neurology
- Phone: 314-747-0286
- Email: holtzman@wustl.edu
Cellular/Molecular/ Biomarker studies of Alzheimer’s Disease and neonatal brain injury
![Song Hu, PhD](https://hopecenter.wustl.edu/files/2021/04/HuSong-280x386.jpg)
Song Hu, PhD
Associate Professor, WashU Biomedical Engineering
- Phone: 314-935-3637
- Email: songhu@wustl.edu
Optical and photoacoustic imaging
![Masatoshi Inoue, PhD](https://hopecenter.wustl.edu/files/2024/02/InoueMasatoshi_web-7b1463e451817c5c-280x386.jpg)
Masatoshi Inoue, PhD
Assistant Professor, WashU Radiology
- Email: inoue.m@wustl.edu
Understanding how the brain processes sensory cues to drive complex behaviors
![Meredith Jackrel, PhD](https://hopecenter.wustl.edu/files/2020/02/jackrelmeredith-chem.jpg)
Meredith Jackrel, PhD
Associate Professor, WashU Chemistry
- Phone: 314-935-6530
- Email: mjackrel@wustl.edu
Engineering and applying protein-remodeling factors to counter neurodegenerative disease
![Sanjay Jain, PhD](https://hopecenter.wustl.edu/files/2020/02/JainSanjay_web-280x386.jpg)
Sanjay Jain, PhD
Professor, WashU Medicine
- Phone: 314-454-8728
- Email: sanjayjain@wustl.edu
GFL-Ret mediated mechanisms in the development, repair and regeneration of the nervous and urogenital systems
![Celeste Karch, PhD](https://hopecenter.wustl.edu/files/2020/01/KarchCeleste_forweb.jpg)
Celeste Karch, PhD
Professor, WashU Psychiatry
- Phone: 314-747-3161
- Email: karchc@wustl.edu
Molecular mechanisms underlying tauopathies
![Jonathan Kipnis, PhD](https://hopecenter.wustl.edu/files/2020/07/KipnisJonathan_forweb-280x386.jpg)
Jonathan Kipnis, PhD
BJC Investigator, Alan A. and Edith L. Wolff Distinguished Professor, WashU Pathology & Immunology
- Phone: 314-273-2288
- Email: kipnis@wustl.edu
Complex interactions between the immune system and the central nervous system (CNS) in health and disease
![Paul Kotzbauer, MD, PhD](https://hopecenter.wustl.edu/files/2020/02/KotzbauerPaul_web-280x386.jpg)
Paul Kotzbauer, MD, PhD
Professor, WashU Neurology
- Email: kotzbauerp@wustl.edu
Mechanisms of neurodegeneration in Parkinson’s disease and related disorders
![Alexxai Kravitz, PhD](https://hopecenter.wustl.edu/files/2020/02/KravitzAlexxai_web-280x386.jpg)
Alexxai Kravitz, PhD
Associate Professor, WashU Psychiatry
- Phone: 314-362-5184
- Email: alexxai@wustl.edu
Basal ganglia contributions to movement
![Geraldine Kress, PhD](https://hopecenter.wustl.edu/files/2020/02/KressGeraldine_web-280x386.jpg)
Geraldine Kress, PhD
Assistant Professor, WashU Neurology
- Phone: 314-362-5503
- Email: kress.g.j@wustl.edu
Role of circadian function on memory during aging and Alzheimer’s disease (AD) progression
![Terrance Kummer, MD, PhD](https://hopecenter.wustl.edu/files/2020/02/KummerTerrance_web.jpg)
Terrance Kummer, MD, PhD
Associate Professor, WashU Neurology
- Phone: 314-362-2999
- Email: kummert@wustl.edu
Mechanisms of neuronal injury in acute brain trauma and its link to neurodegeneration
![Jin-Moo Lee, MD, PhD](https://hopecenter.wustl.edu/files/2020/01/LeeJin-Moo_forweb-280x386.jpg)
Jin-Moo Lee, MD, PhD
Andrew B. & Gretchen P. Jones Professor and Chair, WashU Neurology
- Phone: 314-362-7382
- Email: leejm@wustl.edu
Understanding mechanisms of neurologic disease
![Mingjie Li, MD, PhD](https://hopecenter.wustl.edu/files/2020/02/Li_Mingjie_web-280x386.jpg)
Mingjie Li, MD, PhD
Associate Professor, WashU Neurology
- Phone: 314-747-1123
- Email: lim@wustl.edu
Developing viral vectors for applications in neuroscience
![Tristan Qingyun Li, PhD](https://hopecenter.wustl.edu/files/2020/02/Li-Tristan-Qingyun-2022-280x386.jpg)
Tristan Qingyun Li, PhD
Assistant Professor, WashU Neuroscience
- Phone: 314-273-1422
- Email: qingyunli@wustl.edu
Research Interests:
Microglial biology and neuro-immune interaction underlying brain structure and disease
![Xiaowei Li, PhD](https://hopecenter.wustl.edu/files/2021/07/Li-Xiaowei_web-280x386.jpg)
Xiaowei Li, PhD
Assistant Professor, WashU Surgery
- Phone: 314-454-4894
- Email: xiaoweili@wustl.edu
Bioengineering platforms for nervous tissue regeneration after injuries or diseases
![Yang (Eric) Li, PhD](https://hopecenter.wustl.edu/files/2024/01/LiYangEric-ada8c65f1df00370-280x386.jpg)
Yang (Eric) Li, PhD
Assistant Professor, WashU Neurosurgery
- Email: yeli@wustl.edu
Deciphering how risk variants alter gene regulation in brain diseases with advanced genetic, genomic, and bioinformatic tools
![Brendan Lucey, MD](https://hopecenter.wustl.edu/files/2020/02/LuceyBrendan_web-280x386.jpg)
Brendan Lucey, MD
Professor, WashU Neurology
- Phone: 314-747-3805
- Email: luceyb@wustl.edu
Understanding the relationship between sleep, the amyloid beta diurnal pattern, and Alzheimer’s disease
![Moe Mahjoub, PhD](https://hopecenter.wustl.edu/files/2020/02/MahjoubMoe_web.jpg)
Moe Mahjoub, PhD
Associate Professor, WashU Medicine
- Phone: 314-362-5681
- Email: mmahjoub@wustl.edu
Mechanisms of cell-cell signaling in normal development and neurodegenerative disease
![Soe Mar, MD](https://hopecenter.wustl.edu/files/2020/02/Mar-SoeSoe_web-280x386.jpg)
Soe Mar, MD
Professor, WashU Neurology
- Phone: 314-454-6226
- Email: mars@wustl.edu
Pediatric multiple sclerosis and other white matter diseases, and pediatric migraine
![Helen McNeill, PhD](https://hopecenter.wustl.edu/files/2020/02/McNeill-Helen_web-280x386.jpg)
Helen McNeill, PhD
BJC Investigator, Larry J. Shapiro and Carol-Ann Uetake-Shapiro Professor, WashU Developmental Biology
- Phone: 314-273-3050
- Email: mcneillh@wustl.edu
Understanding how Fat cadherins and the Hippo pathway regulate growth and patterning
![Steven Mennerick, PhD](https://hopecenter.wustl.edu/files/2020/02/MennerickSteven_web-280x386.jpg)
Steven Mennerick, PhD
John P. Feighner Professor of Neuropsychopharmacology, WashU Psychiatry
- Phone: 314-747-2988
- Email: menneris@wustl.edu
Physiology of glutamate and GABA neurotransmission in the CNS
![Timothy Miller, MD, PhD](https://hopecenter.wustl.edu/files/2023/02/MillerTim_web-280x386.jpg)
Timothy Miller, MD, PhD
David Clayson Professor, WashU Neurology
- Phone: 314-362-8169
- Email: miller.t@wustl.edu
New, effective, and safe treatments for neurodegenerative diseases